Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients

Background/Introduction. The single anastomosis sleeve ileal (SASI) bypass is a novel metabolic/bariatric surgery operation based on minigastric bypass operation and Santoro’s operation. Objectives. The aim of this study is to present the clinical outcomes of SASI bypass as a treatment alternative f...

Full description

Saved in:
Bibliographic Details
Main Authors: Ayman Kamal, Mahmoud El Azawy, Tarik A. A. Hassan
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2023/5582940
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832544094628347904
author Ayman Kamal
Mahmoud El Azawy
Tarik A. A. Hassan
author_facet Ayman Kamal
Mahmoud El Azawy
Tarik A. A. Hassan
author_sort Ayman Kamal
collection DOAJ
description Background/Introduction. The single anastomosis sleeve ileal (SASI) bypass is a novel metabolic/bariatric surgery operation based on minigastric bypass operation and Santoro’s operation. Objectives. The aim of this study is to present the clinical outcomes of SASI bypass as a treatment alternative for patients with morbid obesity. Methods. This study was a prospective follow-up of morbidly obese patients who underwent SASI bypass at Helwan University Hospital between March 1, 2019, and March 2020. The surgical procedure involved sleeve gastrectomy, followed by the anastomosis of the ileum, which was brought and hand-sewn 4 cm length side to side with the antrum, at a distance of 250 cm from the ileocecal valve. The data collected for the study included the resolution of comorbidities, incidence of gallstones, and one-year morbidity. Results. The mean age of the studied patients (n = 30) was 44.13 ± 8.9 years. The mean BMI of the studied patients was 47.3 ± 7.6 kg/ht2. All patients were morbidly obese for an average of 24 years. Postoperatively, 48% of the patients (n = 13) developed gallstones (GS), and the formation of GS was significantly higher in patients with longer durations of obesity (P = 0.009) and rapid weight loss. There was a significant decrease in the incidence of GS after 12 months postoperatively (P < 0.05). 63% of the patients (n = 19) had malnutrition, and 15 cases required revision due to the fear of further weight loss. Revision and malnutrition were significantly higher among male patients than female patients and among patients with longer durations of obesity (P ≤ 0.001). Conclusion. The SASI bypass may be an effective bariatric and metabolic surgery that can achieve satisfactory weight loss and improvement in medical comorbidities. However, our study highlights the potential risks of severe malnutrition and unpredictable weight loss; patient selection and duration of obesity may play a role in mitigating these risks.
format Article
id doaj-art-ebaca1e6aba64ce28d9badaf8136e9e2
institution Kabale University
issn 2090-0716
language English
publishDate 2023-01-01
publisher Wiley
record_format Article
series Journal of Obesity
spelling doaj-art-ebaca1e6aba64ce28d9badaf8136e9e22025-02-03T10:59:59ZengWileyJournal of Obesity2090-07162023-01-01202310.1155/2023/5582940Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese PatientsAyman Kamal0Mahmoud El Azawy1Tarik A. A. Hassan2Faculty of MedicineFaculty of MedicineFaculty of MedicineBackground/Introduction. The single anastomosis sleeve ileal (SASI) bypass is a novel metabolic/bariatric surgery operation based on minigastric bypass operation and Santoro’s operation. Objectives. The aim of this study is to present the clinical outcomes of SASI bypass as a treatment alternative for patients with morbid obesity. Methods. This study was a prospective follow-up of morbidly obese patients who underwent SASI bypass at Helwan University Hospital between March 1, 2019, and March 2020. The surgical procedure involved sleeve gastrectomy, followed by the anastomosis of the ileum, which was brought and hand-sewn 4 cm length side to side with the antrum, at a distance of 250 cm from the ileocecal valve. The data collected for the study included the resolution of comorbidities, incidence of gallstones, and one-year morbidity. Results. The mean age of the studied patients (n = 30) was 44.13 ± 8.9 years. The mean BMI of the studied patients was 47.3 ± 7.6 kg/ht2. All patients were morbidly obese for an average of 24 years. Postoperatively, 48% of the patients (n = 13) developed gallstones (GS), and the formation of GS was significantly higher in patients with longer durations of obesity (P = 0.009) and rapid weight loss. There was a significant decrease in the incidence of GS after 12 months postoperatively (P < 0.05). 63% of the patients (n = 19) had malnutrition, and 15 cases required revision due to the fear of further weight loss. Revision and malnutrition were significantly higher among male patients than female patients and among patients with longer durations of obesity (P ≤ 0.001). Conclusion. The SASI bypass may be an effective bariatric and metabolic surgery that can achieve satisfactory weight loss and improvement in medical comorbidities. However, our study highlights the potential risks of severe malnutrition and unpredictable weight loss; patient selection and duration of obesity may play a role in mitigating these risks.http://dx.doi.org/10.1155/2023/5582940
spellingShingle Ayman Kamal
Mahmoud El Azawy
Tarik A. A. Hassan
Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
Journal of Obesity
title Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
title_full Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
title_fullStr Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
title_full_unstemmed Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
title_short Unpredictable Malnutrition and Short-Term Outcomes after Single Anastomosis Sleeve Ileal (SASI) Bypass in Obese Patients
title_sort unpredictable malnutrition and short term outcomes after single anastomosis sleeve ileal sasi bypass in obese patients
url http://dx.doi.org/10.1155/2023/5582940
work_keys_str_mv AT aymankamal unpredictablemalnutritionandshorttermoutcomesaftersingleanastomosissleeveilealsasibypassinobesepatients
AT mahmoudelazawy unpredictablemalnutritionandshorttermoutcomesaftersingleanastomosissleeveilealsasibypassinobesepatients
AT tarikaahassan unpredictablemalnutritionandshorttermoutcomesaftersingleanastomosissleeveilealsasibypassinobesepatients