Alteration in gut microbiota accompanied by increased intestinal permeability and Tfh/Tfr imbalance in patients with active SLE

Alteration in gut microbiota accompanied by increased intestinal permeability and Tfh/Tfr imbalance in patients with active SLE

BackgroundIncreased intestinal permeability and altered intestinal microbiota may influence cytokine regulatory immunity in systemic lupus erythematosus (SLE). This study aimed to elucidate the relationship between intestinal flora alters and follicular helper T cells (Tfh), regulatory T cells (Treg...

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Bibliographic Details
Main Authors: Xiaodi Chu, Shuya Li, Yueying Wang, Dazhen Guo, Nana Zhao, Yuanyuan Han, Qian Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut microbiota
systemic lupus erythematosus
zonulin
Tfh/Tfr
IL-2
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1565416/full
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