Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study
Purpose. To report the distribution of iris conicity (steepness of the iris cone), investigate associated factors, and test whether pseudophakia allows the iris to sink back. Methods. A population-based cross-sectional study was carried out. Ophthalmological examination including objective refractio...
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| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/2190347 |
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| author | Alexander K. Schuster Norbert Pfeiffer Stefan Nickels Andreas Schulz Philipp S. Wild Maria Blettner Karl Lackner Manfred E. Beutel Thomas Münzel Urs Vossmerbaeumer |
| author_facet | Alexander K. Schuster Norbert Pfeiffer Stefan Nickels Andreas Schulz Philipp S. Wild Maria Blettner Karl Lackner Manfred E. Beutel Thomas Münzel Urs Vossmerbaeumer |
| author_sort | Alexander K. Schuster |
| collection | DOAJ |
| description | Purpose. To report the distribution of iris conicity (steepness of the iris cone), investigate associated factors, and test whether pseudophakia allows the iris to sink back. Methods. A population-based cross-sectional study was carried out. Ophthalmological examination including objective refraction, biometry, noncontact tonometry, and Scheimpflug imaging (Pentacam®, Oculus) was performed including automated measurement of iris conicity. 3708 phakic subjects, 144 subjects with bilateral and 39 subjects with unilateral pseudophakia were included. Multivariable analyses were carried out to determine independently associated systemic and ocular factors for iris conicity in phakic eyes. Results. Mean iris conicity was 8.28° ± 3.29° (right eyes). Statistical analysis revealed associations between steeper iris conicity and shallower anterior chamber depth, thicker human lens and higher corneal power in multivariable analysis, while older age was related to a flatter iris conicity. Refraction, axial length, central corneal thickness, pupil diameter, and intraocular pressure were not associated with iris conicity. Pseudophakia resulted in a 5.82° flatter iris conicity than in the fellow phakic eyes. Conclusions. Associations indicate a correlation between iris conicity with risk factors for angle-closure, namely, shallower anterior chamber depth and thicker human lens. In pseudophakic eyes, iris conicity is significantly lower, indicating that cataract surgery flattens the iris. |
| format | Article |
| id | doaj-art-eb9d28c78af74919851863475dde1a26 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-eb9d28c78af74919851863475dde1a262025-02-03T01:26:15ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/21903472190347Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health StudyAlexander K. Schuster0Norbert Pfeiffer1Stefan Nickels2Andreas Schulz3Philipp S. Wild4Maria Blettner5Karl Lackner6Manfred E. Beutel7Thomas Münzel8Urs Vossmerbaeumer9Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyPreventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyPreventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyDepartment of Biomedical Statistics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyInstitute for Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyDZHK (German Center for Cardiovascular Research), Partner Site Rhine-Main, Mainz, GermanyDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, GermanyPurpose. To report the distribution of iris conicity (steepness of the iris cone), investigate associated factors, and test whether pseudophakia allows the iris to sink back. Methods. A population-based cross-sectional study was carried out. Ophthalmological examination including objective refraction, biometry, noncontact tonometry, and Scheimpflug imaging (Pentacam®, Oculus) was performed including automated measurement of iris conicity. 3708 phakic subjects, 144 subjects with bilateral and 39 subjects with unilateral pseudophakia were included. Multivariable analyses were carried out to determine independently associated systemic and ocular factors for iris conicity in phakic eyes. Results. Mean iris conicity was 8.28° ± 3.29° (right eyes). Statistical analysis revealed associations between steeper iris conicity and shallower anterior chamber depth, thicker human lens and higher corneal power in multivariable analysis, while older age was related to a flatter iris conicity. Refraction, axial length, central corneal thickness, pupil diameter, and intraocular pressure were not associated with iris conicity. Pseudophakia resulted in a 5.82° flatter iris conicity than in the fellow phakic eyes. Conclusions. Associations indicate a correlation between iris conicity with risk factors for angle-closure, namely, shallower anterior chamber depth and thicker human lens. In pseudophakic eyes, iris conicity is significantly lower, indicating that cataract surgery flattens the iris.http://dx.doi.org/10.1155/2017/2190347 |
| spellingShingle | Alexander K. Schuster Norbert Pfeiffer Stefan Nickels Andreas Schulz Philipp S. Wild Maria Blettner Karl Lackner Manfred E. Beutel Thomas Münzel Urs Vossmerbaeumer Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study Journal of Ophthalmology |
| title | Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study |
| title_full | Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study |
| title_fullStr | Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study |
| title_full_unstemmed | Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study |
| title_short | Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study |
| title_sort | steeper iris conicity is related to a shallower anterior chamber the gutenberg health study |
| url | http://dx.doi.org/10.1155/2017/2190347 |
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