γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
Protective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantial...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2011/587315 |
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| _version_ | 1832555366480609280 |
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| author | Serena Meraviglia Sary El Daker Francesco Dieli Federico Martini Angelo Martino |
| author_facet | Serena Meraviglia Sary El Daker Francesco Dieli Federico Martini Angelo Martino |
| author_sort | Serena Meraviglia |
| collection | DOAJ |
| description | Protective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on γδ T lymphocytes and their role in tuberculosis immunity. |
| format | Article |
| id | doaj-art-eb8cf8019112490391a0c8fe7e9eac35 |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-eb8cf8019112490391a0c8fe7e9eac352025-02-03T05:48:26ZengWileyClinical and Developmental Immunology1740-25221740-25302011-01-01201110.1155/2011/587315587315γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis InfectionSerena Meraviglia0Sary El Daker1Francesco Dieli2Federico Martini3Angelo Martino4Dipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Università di Palermo, 90134 Palermo, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyDipartimento di Biopatologia e Biotecnologie Mediche e Forensi, Università di Palermo, 90134 Palermo, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyLaboratory of Cellular Immunology, National Institute for Infectious Diseases “Lazzaro Spallanzani” IRCCS, Via Portuense 292, 00149 Rome, ItalyProtective immunity against mycobacterial infections such as Mycobacterium tuberculosis is mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations on γδ T lymphocytes and their role in tuberculosis immunity.http://dx.doi.org/10.1155/2011/587315 |
| spellingShingle | Serena Meraviglia Sary El Daker Francesco Dieli Federico Martini Angelo Martino γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection Clinical and Developmental Immunology |
| title | γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection |
| title_full | γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection |
| title_fullStr | γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection |
| title_full_unstemmed | γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection |
| title_short | γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection |
| title_sort | γδ t cells cross link innate and adaptive immunity in mycobacterium tuberculosis infection |
| url | http://dx.doi.org/10.1155/2011/587315 |
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