Decoding TGR5: A comprehensive review of its impact on cerebral diseases

Decoding TGR5: A comprehensive review of its impact on cerebral diseases

Currently, unraveling the enigmatic realm of drug targets for cerebral disorders poses a formidable challenge. Takeda G protein-coupled receptor 5 (TGR5), also known as G protein-coupled bile acid receptor 1, is a specific bile acid receptor. Widely distributed across various tissues, TGR5 orchestra...

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Bibliographic Details
Main Authors: Zehan Zhang, Yifei Zhang, Hongye Peng, Qingqian Yu, Xiangdong Kang, Ying Liu, Yuxiao Zheng, Fafeng Cheng, Xueqian Wang, Feng Li
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research
Subjects:
TGR5
Cerebral diseases
Biological process
Therapeutic target
Agonist
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825000969
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