Latin America’s Dengue Outbreak Poses a Global Health Threat
Dengue fever, caused by the dengue virus (DENV), poses a significant global health challenge, particularly in tropical and subtropical regions. Recent increases in indigenous DENV cases in Europe are concerning, reflecting rising incidence linked to climate change and the spread of <i>Aedes al...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/17/1/57 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832587398060441600 |
|---|---|
| author | Michelle Teixeira de Almeida Davi Gabriel Salustiano Merighi Aline Biazola Visnardi Cauê Augusto Boneto Gonçalves Vitor Martins de Freitas Amorim Anielle Salviano de Almeida Ferrari Anacleto Silva de Souza Cristiane Rodrigues Guzzo |
| author_facet | Michelle Teixeira de Almeida Davi Gabriel Salustiano Merighi Aline Biazola Visnardi Cauê Augusto Boneto Gonçalves Vitor Martins de Freitas Amorim Anielle Salviano de Almeida Ferrari Anacleto Silva de Souza Cristiane Rodrigues Guzzo |
| author_sort | Michelle Teixeira de Almeida |
| collection | DOAJ |
| description | Dengue fever, caused by the dengue virus (DENV), poses a significant global health challenge, particularly in tropical and subtropical regions. Recent increases in indigenous DENV cases in Europe are concerning, reflecting rising incidence linked to climate change and the spread of <i>Aedes albopictus</i> mosquitoes. These vectors thrive under environmental conditions like temperature and humidity, which are increasingly influenced by climate change. Additionally, global travel accelerates the cross-border spread of mosquito-borne diseases. DENV manifests clinically in a spectrum from asymptomatic cases to severe conditions like dengue hemorrhagic fever and dengue shock syndrome, influenced by viral serotype and host factors. In 2024, Brazil experienced a fourfold increase in dengue cases compared to 2023, accompanied by higher mortality. Conventional control measures, such as vector control, community engagement, and vaccination, proved insufficient as climate change exacerbated mosquito proliferation, challenging containment efforts. In this regard, our review analyzes prevention measures and therapeutic protocols during the outbreak while addressing DENV transmission dynamics, clinical presentations, and epidemiological shifts. It also evaluates diagnostic strategies combining clinical assessment with serological and molecular testing, providing information to improve diagnostic and preventive measures. The global expansion of dengue-endemic regions, including outbreaks in Europe, highlights the urgent need for enhanced surveillance, proactive interventions, and international collaboration to mitigate the growing threat of Dengue and other arboviruses like West Nile, Zika, Chikungunya, Oropouche, and Yellow Fever viruses. |
| format | Article |
| id | doaj-art-eb7fa527071c46ad8553ad2a6b6d2c38 |
| institution | Kabale University |
| issn | 1999-4915 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj-art-eb7fa527071c46ad8553ad2a6b6d2c382025-01-24T13:52:25ZengMDPI AGViruses1999-49152025-01-011715710.3390/v17010057Latin America’s Dengue Outbreak Poses a Global Health ThreatMichelle Teixeira de Almeida0Davi Gabriel Salustiano Merighi1Aline Biazola Visnardi2Cauê Augusto Boneto Gonçalves3Vitor Martins de Freitas Amorim4Anielle Salviano de Almeida Ferrari5Anacleto Silva de Souza6Cristiane Rodrigues Guzzo7Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 5508-900, BrazilDengue fever, caused by the dengue virus (DENV), poses a significant global health challenge, particularly in tropical and subtropical regions. Recent increases in indigenous DENV cases in Europe are concerning, reflecting rising incidence linked to climate change and the spread of <i>Aedes albopictus</i> mosquitoes. These vectors thrive under environmental conditions like temperature and humidity, which are increasingly influenced by climate change. Additionally, global travel accelerates the cross-border spread of mosquito-borne diseases. DENV manifests clinically in a spectrum from asymptomatic cases to severe conditions like dengue hemorrhagic fever and dengue shock syndrome, influenced by viral serotype and host factors. In 2024, Brazil experienced a fourfold increase in dengue cases compared to 2023, accompanied by higher mortality. Conventional control measures, such as vector control, community engagement, and vaccination, proved insufficient as climate change exacerbated mosquito proliferation, challenging containment efforts. In this regard, our review analyzes prevention measures and therapeutic protocols during the outbreak while addressing DENV transmission dynamics, clinical presentations, and epidemiological shifts. It also evaluates diagnostic strategies combining clinical assessment with serological and molecular testing, providing information to improve diagnostic and preventive measures. The global expansion of dengue-endemic regions, including outbreaks in Europe, highlights the urgent need for enhanced surveillance, proactive interventions, and international collaboration to mitigate the growing threat of Dengue and other arboviruses like West Nile, Zika, Chikungunya, Oropouche, and Yellow Fever viruses.https://www.mdpi.com/1999-4915/17/1/57Dengueoutbreakvaccinespandemicepidemiology |
| spellingShingle | Michelle Teixeira de Almeida Davi Gabriel Salustiano Merighi Aline Biazola Visnardi Cauê Augusto Boneto Gonçalves Vitor Martins de Freitas Amorim Anielle Salviano de Almeida Ferrari Anacleto Silva de Souza Cristiane Rodrigues Guzzo Latin America’s Dengue Outbreak Poses a Global Health Threat Viruses Dengue outbreak vaccines pandemic epidemiology |
| title | Latin America’s Dengue Outbreak Poses a Global Health Threat |
| title_full | Latin America’s Dengue Outbreak Poses a Global Health Threat |
| title_fullStr | Latin America’s Dengue Outbreak Poses a Global Health Threat |
| title_full_unstemmed | Latin America’s Dengue Outbreak Poses a Global Health Threat |
| title_short | Latin America’s Dengue Outbreak Poses a Global Health Threat |
| title_sort | latin america s dengue outbreak poses a global health threat |
| topic | Dengue outbreak vaccines pandemic epidemiology |
| url | https://www.mdpi.com/1999-4915/17/1/57 |
| work_keys_str_mv | AT michelleteixeiradealmeida latinamericasdengueoutbreakposesaglobalhealththreat AT davigabrielsalustianomerighi latinamericasdengueoutbreakposesaglobalhealththreat AT alinebiazolavisnardi latinamericasdengueoutbreakposesaglobalhealththreat AT caueaugustobonetogoncalves latinamericasdengueoutbreakposesaglobalhealththreat AT vitormartinsdefreitasamorim latinamericasdengueoutbreakposesaglobalhealththreat AT aniellesalvianodealmeidaferrari latinamericasdengueoutbreakposesaglobalhealththreat AT anacletosilvadesouza latinamericasdengueoutbreakposesaglobalhealththreat AT cristianerodriguesguzzo latinamericasdengueoutbreakposesaglobalhealththreat |