Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract
The stem of Indian borage (Plectranthus amboinicus) was found to be an antioxidant rich fraction as evaluated by in vitro models such as DPPH free radical scavenging, reducing power assay, superoxide anion radical scavenging, and total antioxidant capacity. The extract also exhibited antiplatelet ag...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/320329 |
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| author | Praveena Bhatt Gilbert Stanley Joseph Pradeep Singh Negi Mandyam Chakravarthy Varadaraj |
| author_facet | Praveena Bhatt Gilbert Stanley Joseph Pradeep Singh Negi Mandyam Chakravarthy Varadaraj |
| author_sort | Praveena Bhatt |
| collection | DOAJ |
| description | The stem of Indian borage (Plectranthus amboinicus) was found to be an antioxidant rich fraction as evaluated by in vitro models such as DPPH free radical scavenging, reducing power assay, superoxide anion radical scavenging, and total antioxidant capacity. The extract also exhibited antiplatelet aggregation ability, antibacterial activity, and antiproliferative effect against cancer cell lines: Caco-2, HCT-15, and MCF-7. Phytochemical evaluation of the extract revealed the occurrence of total phenolics (49.91 mg GAE/g extract), total flavonoids (26.6 mg RE/g extract), and condensed tannins (0.7 mg TAE/g extract). Among the major phenolics, rosmarinic acid (6.160 mg/g extract) was predominant, followed by caffeic acid (0.770 mg/g extract), rutin (0.324 mg/g extract), gallic acid (0.260 mg/g extract), quercetin (0.15 mg/g extract), and p-coumaric acid (0.104 mg/g extract). The appreciable biological activity and presence of biomolecules in the methanolic extract of stem indicate its potential application as functional food ingredients and nutraceuticals. |
| format | Article |
| id | doaj-art-eb625ca4640143a0b45649374c64382d |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-eb625ca4640143a0b45649374c64382d2025-02-03T05:46:56ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/320329320329Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem ExtractPraveena Bhatt0Gilbert Stanley Joseph1Pradeep Singh Negi2Mandyam Chakravarthy Varadaraj3Fermentation Technology and Bioengineering, CSIR-Central Food Technological Research Institute, Mysore 570020, IndiaHuman Resource Development, CSIR-Central Food Technological Research Institute, Mysore 570020, IndiaFruit and Vegetable Technology, CSIR-Central Food Technological Research Institute, Mysore 570020, IndiaFood Microbiology, CSIR-Central Food Technological Research Institute, Mysore 570020, IndiaThe stem of Indian borage (Plectranthus amboinicus) was found to be an antioxidant rich fraction as evaluated by in vitro models such as DPPH free radical scavenging, reducing power assay, superoxide anion radical scavenging, and total antioxidant capacity. The extract also exhibited antiplatelet aggregation ability, antibacterial activity, and antiproliferative effect against cancer cell lines: Caco-2, HCT-15, and MCF-7. Phytochemical evaluation of the extract revealed the occurrence of total phenolics (49.91 mg GAE/g extract), total flavonoids (26.6 mg RE/g extract), and condensed tannins (0.7 mg TAE/g extract). Among the major phenolics, rosmarinic acid (6.160 mg/g extract) was predominant, followed by caffeic acid (0.770 mg/g extract), rutin (0.324 mg/g extract), gallic acid (0.260 mg/g extract), quercetin (0.15 mg/g extract), and p-coumaric acid (0.104 mg/g extract). The appreciable biological activity and presence of biomolecules in the methanolic extract of stem indicate its potential application as functional food ingredients and nutraceuticals.http://dx.doi.org/10.1155/2013/320329 |
| spellingShingle | Praveena Bhatt Gilbert Stanley Joseph Pradeep Singh Negi Mandyam Chakravarthy Varadaraj Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract Journal of Chemistry |
| title | Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract |
| title_full | Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract |
| title_fullStr | Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract |
| title_full_unstemmed | Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract |
| title_short | Chemical Composition and Nutraceutical Potential of Indian Borage (Plectranthus amboinicus) Stem Extract |
| title_sort | chemical composition and nutraceutical potential of indian borage plectranthus amboinicus stem extract |
| url | http://dx.doi.org/10.1155/2013/320329 |
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