Genomic characterization of plasmids harboring blaNDM-1, blaNDM-5, and blaNDM-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan

Genomic characterization of plasmids harboring blaNDM-1, blaNDM-5, and blaNDM-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan

ABSTRACT Klebsiella pneumoniae is notorious for causing healthcare-associated infections, which become more complicated by the acquisition of blaNDM genes via mobile genetic elements. Although Pakistan is a well-established hot spot of blaNDM-positive K. pneumoniae, detailed molecular descriptions o...

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Main Authors: Muhammad Usman Qamar, Roberto Sierra, Kokab Jabeen, Muhammad Rizwan, Ayesha Rashid, Yumna Fatima Dar, Diego O. Andrey
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
CR-KP
plasmids
carbapenemases
NDM
antibiotic resistance
mobile genetic elements
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02359-24
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