Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia

Ventilator-associated pneumonia (VAP) is a common and serious infection in the intensive care unit (ICU), closely linked to the microbial environment in the mouth of patients with mechanical ventilation. Chlorhexidine, a widely used oral hygiene disinfectant, may play a role in preventing VAP. Howev...

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Main Authors: PENG Yangyao, CHEN Song, QIN Shuwen, XU Dandan, ZHOU Jianliang, GAO Caixia
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2025-01-01
Series:Yixue xinzhi zazhi
Subjects:
Online Access:https://yxxz.whuznhmedj.com/futureApi/storage/attach/2501/JuQg9u1i0TLI0QaUKPCc2IETjcwj0IN4C6ilawfP.pdf
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author PENG Yangyao
CHEN Song
QIN Shuwen
XU Dandan
ZHOU Jianliang
GAO Caixia
author_facet PENG Yangyao
CHEN Song
QIN Shuwen
XU Dandan
ZHOU Jianliang
GAO Caixia
author_sort PENG Yangyao
collection DOAJ
description Ventilator-associated pneumonia (VAP) is a common and serious infection in the intensive care unit (ICU), closely linked to the microbial environment in the mouth of patients with mechanical ventilation. Chlorhexidine, a widely used oral hygiene disinfectant, may play a role in preventing VAP. However, in recent years, there has been some controversy surrounding the use of chlorhexidine in oral care. This article summarizes the antibacterial mechanism of chlorhexidine, its role in preventing VAP, the effects of chlorhexidine at different concentrations and frequencies in VAP prevention, as well as safety and bacterial resistance issues, to provide reference for the clinical oral care application and related research of chlorhexidine.
format Article
id doaj-art-eb32de21563546299219143068027d16
institution Kabale University
issn 1004-5511
language zho
publishDate 2025-01-01
publisher Editorial Office of New Medicine
record_format Article
series Yixue xinzhi zazhi
spelling doaj-art-eb32de21563546299219143068027d162025-01-25T11:12:53ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112025-01-0135111011510.12173/j.issn.1004-5511.2024080616593Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumoniaPENG YangyaoCHEN SongQIN ShuwenXU DandanZHOU JianliangGAO CaixiaVentilator-associated pneumonia (VAP) is a common and serious infection in the intensive care unit (ICU), closely linked to the microbial environment in the mouth of patients with mechanical ventilation. Chlorhexidine, a widely used oral hygiene disinfectant, may play a role in preventing VAP. However, in recent years, there has been some controversy surrounding the use of chlorhexidine in oral care. This article summarizes the antibacterial mechanism of chlorhexidine, its role in preventing VAP, the effects of chlorhexidine at different concentrations and frequencies in VAP prevention, as well as safety and bacterial resistance issues, to provide reference for the clinical oral care application and related research of chlorhexidine.https://yxxz.whuznhmedj.com/futureApi/storage/attach/2501/JuQg9u1i0TLI0QaUKPCc2IETjcwj0IN4C6ilawfP.pdfchlorhexidineoral careventilator-associated pneumoniamechanical ventilationbacterial resistance
spellingShingle PENG Yangyao
CHEN Song
QIN Shuwen
XU Dandan
ZHOU Jianliang
GAO Caixia
Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
Yixue xinzhi zazhi
chlorhexidine
oral care
ventilator-associated pneumonia
mechanical ventilation
bacterial resistance
title Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
title_full Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
title_fullStr Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
title_full_unstemmed Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
title_short Research progress of chlorhexidine oral care solution for prevention of ventilator-associated pneumonia
title_sort research progress of chlorhexidine oral care solution for prevention of ventilator associated pneumonia
topic chlorhexidine
oral care
ventilator-associated pneumonia
mechanical ventilation
bacterial resistance
url https://yxxz.whuznhmedj.com/futureApi/storage/attach/2501/JuQg9u1i0TLI0QaUKPCc2IETjcwj0IN4C6ilawfP.pdf
work_keys_str_mv AT pengyangyao researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia
AT chensong researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia
AT qinshuwen researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia
AT xudandan researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia
AT zhoujianliang researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia
AT gaocaixia researchprogressofchlorhexidineoralcaresolutionforpreventionofventilatorassociatedpneumonia