Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives
Diabetes mellitus and periodontitis are two of the most common chronic diseases affecting the world’s population, and they are intimately linked. For several years, in fact, it has been known that there is an interdependent relationship between the two diseases: Diabetes promotes the destruction of...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2022/4955277 |
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| author | Simona Santonocito Alessandro Polizzi Enrico Marchetti Domenico Dalessandri Marco Migliorati Saturnino Marco Lupi Marco Cicciù Gaetano Isola |
| author_facet | Simona Santonocito Alessandro Polizzi Enrico Marchetti Domenico Dalessandri Marco Migliorati Saturnino Marco Lupi Marco Cicciù Gaetano Isola |
| author_sort | Simona Santonocito |
| collection | DOAJ |
| description | Diabetes mellitus and periodontitis are two of the most common chronic diseases affecting the world’s population, and they are intimately linked. For several years, in fact, it has been known that there is an interdependent relationship between the two diseases: Diabetes promotes the destruction of periodontal tissues, and periodontal disease negatively affects glycemic control. In relation to the control of dental plaque and oral dysbiosis responsible for periodontal disease, both nonsurgical and surgical therapy associated with proper home hygiene procedures have emerged as essential for good glycemic control. Moreover, several evidences suggest the essential role played by the control of periodontal disease in preventing the onset of the most common complications of diabetes: cardiovascular diseases, retinopathies, and other systemic diseases. The aim of this study is to update the current knowledge on the bi-univocal relationship between diabetes and periodontitis and the impact of therapy in the optimal management of these two disorders. From the information found in the literature, it has emerged that the correct treatment of periodontal disease in diabetic patients represents one of the main mechanisms and means currently established and valid to control periodontal disease and glucose metabolism and prevent the onset or development of diabetic complications. |
| format | Article |
| id | doaj-art-eb28134360cf4ffb9441512aee02b9ba |
| institution | Kabale University |
| issn | 1466-1861 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-eb28134360cf4ffb9441512aee02b9ba2025-02-03T05:50:39ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/4955277Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic PerspectivesSimona Santonocito0Alessandro Polizzi1Enrico Marchetti2Domenico Dalessandri3Marco Migliorati4Saturnino Marco Lupi5Marco Cicciù6Gaetano Isola7Department of General Surgery and Surgical-Medical SpecialtiesDepartment of General Surgery and Surgical-Medical SpecialtiesDepartment of LifeDepartment of Medical and Surgical SpecialtiesDental SchoolUnit of Oral Surgery and ImplantologyDepartment of Biomedical and Dental SciencesDepartment of General Surgery and Surgical-Medical SpecialtiesDiabetes mellitus and periodontitis are two of the most common chronic diseases affecting the world’s population, and they are intimately linked. For several years, in fact, it has been known that there is an interdependent relationship between the two diseases: Diabetes promotes the destruction of periodontal tissues, and periodontal disease negatively affects glycemic control. In relation to the control of dental plaque and oral dysbiosis responsible for periodontal disease, both nonsurgical and surgical therapy associated with proper home hygiene procedures have emerged as essential for good glycemic control. Moreover, several evidences suggest the essential role played by the control of periodontal disease in preventing the onset of the most common complications of diabetes: cardiovascular diseases, retinopathies, and other systemic diseases. The aim of this study is to update the current knowledge on the bi-univocal relationship between diabetes and periodontitis and the impact of therapy in the optimal management of these two disorders. From the information found in the literature, it has emerged that the correct treatment of periodontal disease in diabetic patients represents one of the main mechanisms and means currently established and valid to control periodontal disease and glucose metabolism and prevent the onset or development of diabetic complications.http://dx.doi.org/10.1155/2022/4955277 |
| spellingShingle | Simona Santonocito Alessandro Polizzi Enrico Marchetti Domenico Dalessandri Marco Migliorati Saturnino Marco Lupi Marco Cicciù Gaetano Isola Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives Mediators of Inflammation |
| title | Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives |
| title_full | Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives |
| title_fullStr | Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives |
| title_full_unstemmed | Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives |
| title_short | Impact of Periodontitis on Glycemic Control and Metabolic Status in Diabetes Patients: Current Knowledge on Early Disease Markers and Therapeutic Perspectives |
| title_sort | impact of periodontitis on glycemic control and metabolic status in diabetes patients current knowledge on early disease markers and therapeutic perspectives |
| url | http://dx.doi.org/10.1155/2022/4955277 |
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