Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection
Sarcoidosis is a systemic granulomatous disease that predominantly affects the lungs. However, its presentation as a giant pulmonary bulla is exceptionally rare. Its association with COVID-19 has raised new concerns regarding disease exacerbation and misdiagnosis. We report a case of a 38-year-old m...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-05-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096251340738 |
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| author | Sathish Krishnan MD, FCCP Anam Naumaan MD Venu Pararath Gopalakrishnan MD, FACP |
| author_facet | Sathish Krishnan MD, FCCP Anam Naumaan MD Venu Pararath Gopalakrishnan MD, FACP |
| author_sort | Sathish Krishnan MD, FCCP |
| collection | DOAJ |
| description | Sarcoidosis is a systemic granulomatous disease that predominantly affects the lungs. However, its presentation as a giant pulmonary bulla is exceptionally rare. Its association with COVID-19 has raised new concerns regarding disease exacerbation and misdiagnosis. We report a case of a 38-year-old man who developed a large left lower lobe bulla in the context of recent COVID-19 infection. Initial misinterpretation of the bulla as loculated pneumothorax nearly led to an unnecessary chest tube placement. A subsequent thoracotomy with lobectomy revealed nonnecrotizing granulomas, confirming sarcoidosis. The patient showed spontaneous remission without requiring treatment. This case highlights the importance of multidisciplinary discussions in atypical lung presentations to prevent mismanagement. |
| format | Article |
| id | doaj-art-eb26b67ea0914f30934e82910ec0d37f |
| institution | OA Journals |
| issn | 2324-7096 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj-art-eb26b67ea0914f30934e82910ec0d37f2025-08-20T02:28:19ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962025-05-011310.1177/23247096251340738Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 InfectionSathish Krishnan MD, FCCP0Anam Naumaan MD1Venu Pararath Gopalakrishnan MD, FACP2Division of Pulmonary and Critical Care Medicine, Community Health Network, Indianapolis, IN, USADivision of Pathology, Community Health Network, Indianapolis, IN, USADivision of Hospital Medicine, University of Massachusetts Chan Medical School, Worcester, USASarcoidosis is a systemic granulomatous disease that predominantly affects the lungs. However, its presentation as a giant pulmonary bulla is exceptionally rare. Its association with COVID-19 has raised new concerns regarding disease exacerbation and misdiagnosis. We report a case of a 38-year-old man who developed a large left lower lobe bulla in the context of recent COVID-19 infection. Initial misinterpretation of the bulla as loculated pneumothorax nearly led to an unnecessary chest tube placement. A subsequent thoracotomy with lobectomy revealed nonnecrotizing granulomas, confirming sarcoidosis. The patient showed spontaneous remission without requiring treatment. This case highlights the importance of multidisciplinary discussions in atypical lung presentations to prevent mismanagement.https://doi.org/10.1177/23247096251340738 |
| spellingShingle | Sathish Krishnan MD, FCCP Anam Naumaan MD Venu Pararath Gopalakrishnan MD, FACP Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection Journal of Investigative Medicine High Impact Case Reports |
| title | Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection |
| title_full | Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection |
| title_fullStr | Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection |
| title_full_unstemmed | Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection |
| title_short | Sarcoidosis Presenting as a Giant Pulmonary Bulla With Concurrent COVID-19 Infection |
| title_sort | sarcoidosis presenting as a giant pulmonary bulla with concurrent covid 19 infection |
| url | https://doi.org/10.1177/23247096251340738 |
| work_keys_str_mv | AT sathishkrishnanmdfccp sarcoidosispresentingasagiantpulmonarybullawithconcurrentcovid19infection AT anamnaumaanmd sarcoidosispresentingasagiantpulmonarybullawithconcurrentcovid19infection AT venupararathgopalakrishnanmdfacp sarcoidosispresentingasagiantpulmonarybullawithconcurrentcovid19infection |