Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index

In children with persistent asthma, inhaled glucocorticoids decrease symptoms and exacerbations, decrease the need for rescue bronchodilator medications, improve airway patency and reduce airway hyperresponsiveness. When administered in the lowest doses that prevent symptoms and eliminate the need f...

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Main Author: F Estelle R Simons
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/1999/957127
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author F Estelle R Simons
author_facet F Estelle R Simons
author_sort F Estelle R Simons
collection DOAJ
description In children with persistent asthma, inhaled glucocorticoids decrease symptoms and exacerbations, decrease the need for rescue bronchodilator medications, improve airway patency and reduce airway hyperresponsiveness. When administered in the lowest doses that prevent symptoms and eliminate the need for supplemental courses of oral glucocorticoids, they are unlikely to cause clinically important systemic adverse events. Inhaled glucocorticoids have a favourable risk to benefit ratio in this population.
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spelling doaj-art-eb1807a7fa684b4a854d8ce3e806ea062025-02-03T05:52:50ZengWileyCanadian Respiratory Journal1198-22411999-01-016217517810.1155/1999/957127Inhaled Glucocoriticoids in Children: A Facourable Therapeutic IndexF Estelle R Simons0Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, CanadaIn children with persistent asthma, inhaled glucocorticoids decrease symptoms and exacerbations, decrease the need for rescue bronchodilator medications, improve airway patency and reduce airway hyperresponsiveness. When administered in the lowest doses that prevent symptoms and eliminate the need for supplemental courses of oral glucocorticoids, they are unlikely to cause clinically important systemic adverse events. Inhaled glucocorticoids have a favourable risk to benefit ratio in this population.http://dx.doi.org/10.1155/1999/957127
spellingShingle F Estelle R Simons
Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
Canadian Respiratory Journal
title Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
title_full Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
title_fullStr Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
title_full_unstemmed Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
title_short Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index
title_sort inhaled glucocoriticoids in children a facourable therapeutic index
url http://dx.doi.org/10.1155/1999/957127
work_keys_str_mv AT festellersimons inhaledglucocoriticoidsinchildrenafacourabletherapeuticindex