Dysregulation of proBDNF/p75NTR and BDNF/TrkB Signaling in Acute Ischemic Stroke: Different Sides of the Same Coins

Dysregulation of proBDNF/p75NTR and BDNF/TrkB Signaling in Acute Ischemic Stroke: Different Sides of the Same Coins

Acute ischemic stroke (AIS) is a focal neurological deficit due to sudden occlusion of cerebral vessels in the brain. AIS-induced neuronal injury and associated excite-toxicity and neurodegeneration affect the synthesis and the release of different neurotrophic factors such as brain-derived neurotro...

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Bibliographic Details
Main Authors: Hala Alnoaman, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Areej Turkistani, Albatoul Allam, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Brain Research Bulletin
Subjects:
Acute ischemic stroke
ProBDNF
BDNF
BDNF-TrkB signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025001509
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