Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development
Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2018/4601420 |
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| _version_ | 1832564858489405440 |
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| author | Micaella Kantor Anarella Abrantes Andrea Estevez Alan Schiller Jose Torrent Jose Gascon Robert Hernandez Christopher Ochner |
| author_facet | Micaella Kantor Anarella Abrantes Andrea Estevez Alan Schiller Jose Torrent Jose Gascon Robert Hernandez Christopher Ochner |
| author_sort | Micaella Kantor |
| collection | DOAJ |
| description | Entamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host’s immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine. |
| format | Article |
| id | doaj-art-eaf7f0c30d52496281d01ea5963fc6db |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-eaf7f0c30d52496281d01ea5963fc6db2025-02-03T01:10:07ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972018-01-01201810.1155/2018/46014204601420Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine DevelopmentMicaella Kantor0Anarella Abrantes1Andrea Estevez2Alan Schiller3Jose Torrent4Jose Gascon5Robert Hernandez6Christopher Ochner7Kendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAKendall Regional Medical Center, Miami, FL, USAHospital Corporation of America, East Florida Division, Fort Lauderdale, FL, USAEntamoeba histolytica is the responsible parasite of amoebiasis and remains one of the top three parasitic causes of mortality worldwide. With increased travel and emigration to developed countries, infection is becoming more common in nonendemic areas. Although the majority of individuals infected with E. histolytica remain asymptomatic, some present with amoebic colitis and disseminated disease. As more is learned about its pathogenesis and the host’s immune response, the potential for developing a vaccine holds promise. This narrative review outlines the current knowledge regarding E. histolytica and E. dispar and insight in the development of a vaccine.http://dx.doi.org/10.1155/2018/4601420 |
| spellingShingle | Micaella Kantor Anarella Abrantes Andrea Estevez Alan Schiller Jose Torrent Jose Gascon Robert Hernandez Christopher Ochner Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development Canadian Journal of Gastroenterology and Hepatology |
| title | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
| title_full | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
| title_fullStr | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
| title_full_unstemmed | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
| title_short | Entamoeba Histolytica: Updates in Clinical Manifestation, Pathogenesis, and Vaccine Development |
| title_sort | entamoeba histolytica updates in clinical manifestation pathogenesis and vaccine development |
| url | http://dx.doi.org/10.1155/2018/4601420 |
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