High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy

Highlights Fe single-atom catalysts (h3-FNCs) with high loading, high catalytic activity and high stability were synthesized via a method capable of increasing both the metal loading and mass-specific activity by exchanging zinc with iron. The “density effect,” derived from the sufficiently high den...

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Main Authors: Si Chen, Fang Huang, Lijie Mao, Zhimin Zhang, Han Lin, Qixin Yan, Xiangyu Lu, Jianlin Shi
Format: Article
Language:English
Published: SpringerOpen 2024-10-01
Series:Nano-Micro Letters
Subjects:
Online Access:https://doi.org/10.1007/s40820-024-01522-1
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author Si Chen
Fang Huang
Lijie Mao
Zhimin Zhang
Han Lin
Qixin Yan
Xiangyu Lu
Jianlin Shi
author_facet Si Chen
Fang Huang
Lijie Mao
Zhimin Zhang
Han Lin
Qixin Yan
Xiangyu Lu
Jianlin Shi
author_sort Si Chen
collection DOAJ
description Highlights Fe single-atom catalysts (h3-FNCs) with high loading, high catalytic activity and high stability were synthesized via a method capable of increasing both the metal loading and mass-specific activity by exchanging zinc with iron. The “density effect,” derived from the sufficiently high density of active sites, has been discovered for the first time, leading to a significant alteration in the intrinsic activity of single-atom metal sites. The superior oxidase-like catalytic performance of h3-FNCs ensures highly effective bacterial eradication.
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institution DOAJ
issn 2311-6706
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language English
publishDate 2024-10-01
publisher SpringerOpen
record_format Article
series Nano-Micro Letters
spelling doaj-art-eaee81a0ab7842139b8f096d622f35ad2025-08-20T03:05:56ZengSpringerOpenNano-Micro Letters2311-67062150-55512024-10-0117111710.1007/s40820-024-01522-1High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial TherapySi Chen0Fang Huang1Lijie Mao2Zhimin Zhang3Han Lin4Qixin Yan5Xiangyu Lu6Jianlin Shi7Department of Cardiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Cardiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Cardiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji UniversityShanghai Institute of Ceramics, Chinese Academy of SciencesShanghai Institute of Ceramics, Chinese Academy of SciencesDepartment of Cardiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Cardiology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji UniversityShanghai Institute of Ceramics, Chinese Academy of SciencesHighlights Fe single-atom catalysts (h3-FNCs) with high loading, high catalytic activity and high stability were synthesized via a method capable of increasing both the metal loading and mass-specific activity by exchanging zinc with iron. The “density effect,” derived from the sufficiently high density of active sites, has been discovered for the first time, leading to a significant alteration in the intrinsic activity of single-atom metal sites. The superior oxidase-like catalytic performance of h3-FNCs ensures highly effective bacterial eradication.https://doi.org/10.1007/s40820-024-01522-1Nanocatalytic medicineSingle-atom catalystsReactive oxygen species (ROS)High metal loadingOxidase catalysis
spellingShingle Si Chen
Fang Huang
Lijie Mao
Zhimin Zhang
Han Lin
Qixin Yan
Xiangyu Lu
Jianlin Shi
High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
Nano-Micro Letters
Nanocatalytic medicine
Single-atom catalysts
Reactive oxygen species (ROS)
High metal loading
Oxidase catalysis
title High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
title_full High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
title_fullStr High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
title_full_unstemmed High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
title_short High Fe-Loading Single-Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
title_sort high fe loading single atom catalyst boosts ros production by density effect for efficient antibacterial therapy
topic Nanocatalytic medicine
Single-atom catalysts
Reactive oxygen species (ROS)
High metal loading
Oxidase catalysis
url https://doi.org/10.1007/s40820-024-01522-1
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