A bivalent mRNA vaccine against RSV infection in rodent models

A bivalent mRNA vaccine against RSV infection in rodent models

Because of the higher conservation of RSV Fusion (F) protein than the glycoprotein (G) across RSV strains and serotypes, the majority of vaccine candidates targets to viral fusion protein (F) rather than glycoprotein to elicit a broader range of protective neutralizing antibodies from infection. In...

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Bibliographic Details
Main Authors: Juan Liu, Hanqing Zhao, Wenhao Wang, Binbin Yang, Naifang Zhang, Yu Zhang, Jie Qian, Qiaofang Ma, Yankun Lu, Huafeng Han, Yongsheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
RSV prefusion protein
mRNA vaccines
neutralizing antibody
protection
immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1542592/full
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