Neoadjuvant Topical Mitomycin C for an Extensive Ocular Surface Squamous Neoplasia

A sixty-five-year old male presented with an enlarging mass over the ocular surface involving nasal area of conjunctiva, superior and inferior fornix and covering the corneal surface obscuring pupil barring a temporal island of cornea. On the basis of clinical features and impression cytology, the d...

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Bibliographic Details
Main Authors: Vaibhav Kumar Jain, Jaya Kaushik, Savita Agarwal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-10-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.503
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Summary:A sixty-five-year old male presented with an enlarging mass over the ocular surface involving nasal area of conjunctiva, superior and inferior fornix and covering the corneal surface obscuring pupil barring a temporal island of cornea. On the basis of clinical features and impression cytology, the diagnosis of ocular surface squamous neoplasia (OSSN) was made and patient was given neoadjuvant chemotherapy in the form of topical mitomycin C (0.04%) for 6 cycles. Excision biopsy with cryotherapy and amniotic membrane transplantation was performed. At the last follow-up, patient showed no clinical evidence of OSSN.
ISSN:0972-0200
2454-2784