The efficacy and safety of rhGH treatment combined with letrozole/GnRHa in adolescent boys

The efficacy and safety of rhGH treatment combined with letrozole/GnRHa in adolescent boys

Abstract Objective In boys during puberty who were undergoing recombinant human growth hormone (rhGH) treatment, we compared the therapeutic efficacy on growth, and any adverse reactions, of co-therapy with either letrozole or gonadotropin-releasing hormone analog (GnRHa). Methods Fifty-six pubertal...

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Bibliographic Details
Main Authors: Ying Zhang, Xin Yuan, Kenneth McCormick, Xiao-Hong Yang, Shi-Jun Chen, Rui-Min Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Pediatrics
Subjects:
Letrozole
Recombinant human growth hormone
Gonadotropin releasing
Adolescent boys
Short stature
Growth hormone deficiency
Online Access:https://doi.org/10.1186/s12887-025-05408-y
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