Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft

We present a case of a patient with a failed pancreaticoduodenal allograft with exocrine enteric-drainage who developed catastrophic gastrointestinal (GI) hemorrhage. Over the course of a week, she presented with recurrent GI bleeds of obscure etiology. Multiple esophago-gastro-duodenoscopic (EGD) a...

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Main Authors: Nirmit Desai, Sagar Patel, Chinyere Nwosu, Lok Sung, Carl Tack, Jonathan M. Buscaglia, Edward P. Nord, Nand K. Wadhwa
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2013/171807
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author Nirmit Desai
Sagar Patel
Chinyere Nwosu
Lok Sung
Carl Tack
Jonathan M. Buscaglia
Edward P. Nord
Nand K. Wadhwa
author_facet Nirmit Desai
Sagar Patel
Chinyere Nwosu
Lok Sung
Carl Tack
Jonathan M. Buscaglia
Edward P. Nord
Nand K. Wadhwa
author_sort Nirmit Desai
collection DOAJ
description We present a case of a patient with a failed pancreaticoduodenal allograft with exocrine enteric-drainage who developed catastrophic gastrointestinal (GI) hemorrhage. Over the course of a week, she presented with recurrent GI bleeds of obscure etiology. Multiple esophago-gastro-duodenoscopic (EGD) and colonoscopic evaluations failed to reveal the source of the hemorrhage. A capsule endoscopy and a technetium-labeled red blood cells (RBC) imaging study were similarly unrevealing for source of bleeding. She subsequently developed hemorrhagic shock requiring emergent superior mesenteric arteriography. Run off images revealed an external iliac artery aneurysm with fistulization into the jejunum. Coiled embolization was attempted but abandoned because of hemodynamic instability. Deployment of a covered endovascular stent into the right external iliac artery over the fistula site resulted in immediate hemodynamic stabilization. A high index of suspicion for arterioenteric fistulae is needed for diagnosis of this uncommon but eminently treatable form of GI hemorrhage in this patient population.
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institution Kabale University
issn 2090-6943
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language English
publishDate 2013-01-01
publisher Wiley
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series Case Reports in Transplantation
spelling doaj-art-eaa4ba204b244c2fab72bf6f151c26072025-02-03T05:45:34ZengWileyCase Reports in Transplantation2090-69432090-69512013-01-01201310.1155/2013/171807171807Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas AllograftNirmit Desai0Sagar Patel1Chinyere Nwosu2Lok Sung3Carl Tack4Jonathan M. Buscaglia5Edward P. Nord6Nand K. Wadhwa7Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USADivision of Nephrology, Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USADivisions of Gastro-Enterology, Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USADepartment of Radiology, Stony Brook Medicine, Stony Brook, NY 11794, USADepartment of Radiology, Stony Brook Medicine, Stony Brook, NY 11794, USADivisions of Gastro-Enterology, Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USADivision of Nephrology, Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USADivision of Nephrology, Department of Medicine, Stony Brook Medicine, Stony Brook, NY 11794, USAWe present a case of a patient with a failed pancreaticoduodenal allograft with exocrine enteric-drainage who developed catastrophic gastrointestinal (GI) hemorrhage. Over the course of a week, she presented with recurrent GI bleeds of obscure etiology. Multiple esophago-gastro-duodenoscopic (EGD) and colonoscopic evaluations failed to reveal the source of the hemorrhage. A capsule endoscopy and a technetium-labeled red blood cells (RBC) imaging study were similarly unrevealing for source of bleeding. She subsequently developed hemorrhagic shock requiring emergent superior mesenteric arteriography. Run off images revealed an external iliac artery aneurysm with fistulization into the jejunum. Coiled embolization was attempted but abandoned because of hemodynamic instability. Deployment of a covered endovascular stent into the right external iliac artery over the fistula site resulted in immediate hemodynamic stabilization. A high index of suspicion for arterioenteric fistulae is needed for diagnosis of this uncommon but eminently treatable form of GI hemorrhage in this patient population.http://dx.doi.org/10.1155/2013/171807
spellingShingle Nirmit Desai
Sagar Patel
Chinyere Nwosu
Lok Sung
Carl Tack
Jonathan M. Buscaglia
Edward P. Nord
Nand K. Wadhwa
Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
Case Reports in Transplantation
title Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
title_full Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
title_fullStr Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
title_full_unstemmed Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
title_short Arteriojejunal Fistula Presenting with Recurrent Obscure GI Hemorrhage in a Patient with a Failed Pancreas Allograft
title_sort arteriojejunal fistula presenting with recurrent obscure gi hemorrhage in a patient with a failed pancreas allograft
url http://dx.doi.org/10.1155/2013/171807
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