Advanced Nanopharmaceutical Intervention for the Reduction of Inflammatory Responses and the Enhancement of Behavioral Outcomes in APP/PS1 Transgenic Mouse Models

Advanced Nanopharmaceutical Intervention for the Reduction of Inflammatory Responses and the Enhancement of Behavioral Outcomes in APP/PS1 Transgenic Mouse Models

<b>Background</b>: The excessive accumulation of Aβ plays a critical role in the development of Alzheimer’s disease. However, the therapeutic potential of drugs like curcumin is often limited by low biocompatibility and BBB permeability. In this study, we developed a nanomaterial, BP-PEG...

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Bibliographic Details
Main Authors: Jun Li, Dongqing Huang, Wanchen Liao, Yulin Wang, Yibiao Liu, Ping Luan
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
Alzheimer’s disease
curcumin
black phosphorus
inhibition of Aβ aggregation
4-(Dimethylamino) cinnamic acid
Online Access:https://www.mdpi.com/1999-4923/17/2/177
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