A midbrain circuit mechanism for noise-induced negative valence coding

A midbrain circuit mechanism for noise-induced negative valence coding

Abstract Unpleasant sounds elicit a range of negative emotional reactions, yet the underlying neural mechanisms remain largely unknown. Here we show that glutamatergic neurons in the central inferior colliculus (CICglu) relay noise information to GABAergic neurons in the ventral tegmental area (VTAG...

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Main Authors: Siyao Zhou, Yuebin Zhu, Ana Du, Shuai Niu, Yonglan Du, Yan Yang, Wenqiang Chen, Siyu Du, Li Sun, Yijun Liu, Hangjun Wu, Huifang Lou, Xiao-Ming Li, Shumin Duan, Hongbin Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59956-z
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