MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS
The new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP st...
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2015-08-01
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| Series: | Детские инфекции (Москва) |
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| Online Access: | https://detinf.elpub.ru/jour/article/view/113 |
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| author | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin |
| author_facet | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin |
| author_sort | G. A. Ivashinnikova |
| collection | DOAJ |
| description | The new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP structural particularities. The developed method for genotyping of strains of B. pertussis can be hhelpful when monitoring strains of the causative agent of whooping cough in system of an epidemiological surveillance over pertussis infections, allowing observation over circulating population of B.pertussis, revealing strains of the causative agent of whooping cough with high production of pertussis toxin and to watch their distribution. |
| format | Article |
| id | doaj-art-ea61dc2f936b4e5c950caed82c2d8872 |
| institution | DOAJ |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2015-08-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-ea61dc2f936b4e5c950caed82c2d88722025-08-20T03:15:22ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-01121343610.22627/2072-8107-2013-12-1-34-36113MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSISG. A. Ivashinnikova0O. U. Borisova1A. V. Aleshkin2A. S. Pimenova3V. A. Aleshkin4Moscow Scientific Research Institute of Epidemiology and Microbiology named after G.N. GabrichevskyMoscow Scientific Research Institute of Epidemiology and Microbiology named after G.N. GabrichevskyMoscow Scientific Research Institute of Epidemiology and Microbiology named after G.N. GabrichevskyMoscow Scientific Research Institute of Epidemiology and Microbiology named after G.N. GabrichevskyMoscow Scientific Research Institute of Epidemiology and Microbiology named after G.N. GabrichevskyThe new rapid molecular genotyping method was developed for studying the structure of ptxP promoter of pertussis toxin. Method is based on PCR-RFLP analysis, which allows studying the specific restriction profiles of the B. pertussis strains and allows differentiation of the strains with the ptxP structural particularities. The developed method for genotyping of strains of B. pertussis can be hhelpful when monitoring strains of the causative agent of whooping cough in system of an epidemiological surveillance over pertussis infections, allowing observation over circulating population of B.pertussis, revealing strains of the causative agent of whooping cough with high production of pertussis toxin and to watch their distribution.https://detinf.elpub.ru/jour/article/view/113b. pertussis, restriction analysis, pertussis toxin promoter |
| spellingShingle | G. A. Ivashinnikova O. U. Borisova A. V. Aleshkin A. S. Pimenova V. A. Aleshkin MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS Детские инфекции (Москва) b. pertussis, restriction analysis, pertussis toxin promoter |
| title | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_full | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_fullStr | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_full_unstemmed | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_short | MODERNIZATION OF GENEOTIPING OF STRAINS B. PERTUSSIS |
| title_sort | modernization of geneotiping of strains b pertussis |
| topic | b. pertussis, restriction analysis, pertussis toxin promoter |
| url | https://detinf.elpub.ru/jour/article/view/113 |
| work_keys_str_mv | AT gaivashinnikova modernizationofgeneotipingofstrainsbpertussis AT ouborisova modernizationofgeneotipingofstrainsbpertussis AT avaleshkin modernizationofgeneotipingofstrainsbpertussis AT aspimenova modernizationofgeneotipingofstrainsbpertussis AT vaaleshkin modernizationofgeneotipingofstrainsbpertussis |