Selective blockade of acid-sensing ion channel 1a can provide substantial hippocampal neuroprotection
BackgroundAcid-sensing ion channel 1a (ASIC1a) is the only member of the ASIC family where Ca2+ osmosis has been reported, and it is highly expressed in neurons of the central nervous system. This study aimed to investigate whether ASIC1a is trafficked to the plasma membrane and regulated by the Rho...
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| Main Authors: | Jiaai Li, Yu Cheng, Di Ma, Guangjian Li, Weixuan Zhao, Ting Jiang, Hongmei Meng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1582970/full |
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