Regulation of Helicobacter pylori Urease and Acetone Carboxylase Genes by Nitric Oxide and the CrdRS Two-Component System

Regulation of Helicobacter pylori Urease and Acetone Carboxylase Genes by Nitric Oxide and the CrdRS Two-Component System

ABSTRACT Helicobacter pylori colonizes the human gastric mucosa and causes various gastroduodenal diseases, including peptic ulceration and gastric cancer. Colonization requires the actions of two-component systems (TCSs) to sense and respond to changes in the host environment. In this study, we eva...

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Bibliographic Details
Main Authors: Madison G. McKinsey, Miranda Y. Bate, Lauren M. Tramonte, Emely Y. Avalos, John Loh, Timothy L. Cover, Mark H. Forsyth
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
Helicobacter
gene regulation
two-component system
urease
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04633-22
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