Extrapulmonary sarcoidosis presenting as myositis: A rare case
Sarcoidosis is a multisystem disease with dominant pulmonary involvement (90%). Isolated extrapulmonary involvement is less common. Skeletal muscle (1-2%) involvement is even rare. We report a 40 year old lady presented with easy fatigability, low grade fever for 5-6 months and generalized myalgias....
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=366;epage=369;aulast=Bohania |
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| author | Niraj Bohania Sumeet Singla Jagriti Nahata Pijush Kanti Nandi Seema Daksh S Anuradha |
| author_facet | Niraj Bohania Sumeet Singla Jagriti Nahata Pijush Kanti Nandi Seema Daksh S Anuradha |
| author_sort | Niraj Bohania |
| collection | DOAJ |
| description | Sarcoidosis is a multisystem disease with dominant pulmonary involvement (90%). Isolated extrapulmonary involvement is less common. Skeletal muscle (1-2%) involvement is even rare. We report a 40 year old lady presented with easy fatigability, low grade fever for 5-6 months and generalized myalgias. Examination revealed pallor, a receding hair line, hepatomegaly and proximal muscle weakness. Investigations revealed anemia, hypercalcemia and raised serum ACE level. During hospital stay patient developed right sided hemiparesis (acute vasculitic infarct in left parietal cortex). A FDG-PET scan was done which revealed that the muscles of upper and lower limbs showed diffuse, heterogenous areas of increased FDG avidity suggestive of myositis. Final diagnosis of extrapulmonary sarcoidosis (presenting as myositis along with CNS vasculitis and hypercalcemia) was made. Patient showed marked improvement in her symptoms with immunosuppressive therapy. This case is a rare manifestation of extrapulmonary sarcoidosis and emphasizes the role of FDG-PET in diagnosing these cases. |
| format | Article |
| id | doaj-art-ea3a2f679bca4913969df96434166df6 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-ea3a2f679bca4913969df96434166df62025-02-03T10:55:03ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012020-01-0115436636910.4103/injr.injr_4_20Extrapulmonary sarcoidosis presenting as myositis: A rare caseNiraj BohaniaSumeet SinglaJagriti NahataPijush Kanti NandiSeema DakshS AnuradhaSarcoidosis is a multisystem disease with dominant pulmonary involvement (90%). Isolated extrapulmonary involvement is less common. Skeletal muscle (1-2%) involvement is even rare. We report a 40 year old lady presented with easy fatigability, low grade fever for 5-6 months and generalized myalgias. Examination revealed pallor, a receding hair line, hepatomegaly and proximal muscle weakness. Investigations revealed anemia, hypercalcemia and raised serum ACE level. During hospital stay patient developed right sided hemiparesis (acute vasculitic infarct in left parietal cortex). A FDG-PET scan was done which revealed that the muscles of upper and lower limbs showed diffuse, heterogenous areas of increased FDG avidity suggestive of myositis. Final diagnosis of extrapulmonary sarcoidosis (presenting as myositis along with CNS vasculitis and hypercalcemia) was made. Patient showed marked improvement in her symptoms with immunosuppressive therapy. This case is a rare manifestation of extrapulmonary sarcoidosis and emphasizes the role of FDG-PET in diagnosing these cases.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=366;epage=369;aulast=Bohaniaextrapulmonary sarcoidosismyositiscentral nervous system vasculitisfluorodeoxyglucose positron emission tomography |
| spellingShingle | Niraj Bohania Sumeet Singla Jagriti Nahata Pijush Kanti Nandi Seema Daksh S Anuradha Extrapulmonary sarcoidosis presenting as myositis: A rare case Indian Journal of Rheumatology extrapulmonary sarcoidosis myositis central nervous system vasculitis fluorodeoxyglucose positron emission tomography |
| title | Extrapulmonary sarcoidosis presenting as myositis: A rare case |
| title_full | Extrapulmonary sarcoidosis presenting as myositis: A rare case |
| title_fullStr | Extrapulmonary sarcoidosis presenting as myositis: A rare case |
| title_full_unstemmed | Extrapulmonary sarcoidosis presenting as myositis: A rare case |
| title_short | Extrapulmonary sarcoidosis presenting as myositis: A rare case |
| title_sort | extrapulmonary sarcoidosis presenting as myositis a rare case |
| topic | extrapulmonary sarcoidosis myositis central nervous system vasculitis fluorodeoxyglucose positron emission tomography |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2020;volume=15;issue=4;spage=366;epage=369;aulast=Bohania |
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