Neuroinflammation and stress-induced pathophysiology in major depressive disorder: mechanisms and therapeutic implications

Neuroinflammation and stress-induced pathophysiology in major depressive disorder: mechanisms and therapeutic implications

Major depressive disorder (MDD) is one of the most common mental health conditions, characterized by pervasive and persistent low mood, low self-esteem, and a loss of interest or pleasure in activities that are typically enjoyable. Despite decades of research into the etiology and pathophysiological...

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Bibliographic Details
Main Authors: Kunying Zhao, Yuxiao Zhang, Shuda Yang, Lirong Xiang, Shangpeng Wu, Junfang Dong, Huan Li, Haofei Yu, Weiyan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
depression
neuroinflammation
microglia
astrocytes
anti-inflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1538026/full
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