Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes

Objectives. The objectives of this study are to assess the efficacy of radiofrequency catheter ablation (RFCA) in patients with outflow tract (OT) ventricular premature complexes (VPCs) and to explore the electrocardiographic (ECG) features of initially successful procedures. Methods. Based on the o...

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Main Authors: Zhen Ye, Zhe Xu, Kezeng Gong, Xuehai Chen, Weiwei Wang, Jianhua Chen, Lianglong Chen, Feilong Zhang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2022/8160144
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author Zhen Ye
Zhe Xu
Kezeng Gong
Xuehai Chen
Weiwei Wang
Jianhua Chen
Lianglong Chen
Feilong Zhang
author_facet Zhen Ye
Zhe Xu
Kezeng Gong
Xuehai Chen
Weiwei Wang
Jianhua Chen
Lianglong Chen
Feilong Zhang
author_sort Zhen Ye
collection DOAJ
description Objectives. The objectives of this study are to assess the efficacy of radiofrequency catheter ablation (RFCA) in patients with outflow tract (OT) ventricular premature complexes (VPCs) and to explore the electrocardiographic (ECG) features of initially successful procedures. Methods. Based on the outcome of ablation, 154 consecutive patients with OT-VPCs who underwent RFCA from January 2017 to December 2019 were divided into two groups. The rate of successful procedures and the ECG features were analyzed and compared between the two groups. Results. The highest success rate was found in patients with VPCs from the right ventricular outflow tract (RVOT), and the lowest success rate was evident among patients with complexes from both the RVOT and the left ventricular OT (LVOT). The patients with successful procedures (136) reflected a lower pseudo delta wave ratio (16.2% vs. 44.4%, P<0.01), a smaller R-wave amplitude in lead V1 (V1) (0.23±0.24 mV vs. 0.35±0.44 mV, P<0.05), shorter intrinsicoid deflection time in lead V2 (V2) (44.00±18.33 ms vs. 57.41±20.67 ms, P<0.01), a shorter RS duration in V2 (93.67±21.33 ms vs. 106.93±18.76 ms, P<0.01), and smaller R/S-waveratios in V2. Furthermore, multivariate analysis demonstrated that RS duration in V2 was above 109.17 ms and R/S ratio in V2 was above 0.28, forecasting a failed procedure. Conclusions. The ECG predictors of failed ablation were characterized by RS duration and R/S ratio in V2.
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spelling doaj-art-ea198e1b3ec54ee8a870abc8641326802025-02-03T06:04:45ZengWileyCardiovascular Therapeutics1755-59222022-01-01202210.1155/2022/8160144Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature ComplexesZhen Ye0Zhe Xu1Kezeng Gong2Xuehai Chen3Weiwei Wang4Jianhua Chen5Lianglong Chen6Feilong Zhang7Department of RheumatologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyDepartment of CardiologyObjectives. The objectives of this study are to assess the efficacy of radiofrequency catheter ablation (RFCA) in patients with outflow tract (OT) ventricular premature complexes (VPCs) and to explore the electrocardiographic (ECG) features of initially successful procedures. Methods. Based on the outcome of ablation, 154 consecutive patients with OT-VPCs who underwent RFCA from January 2017 to December 2019 were divided into two groups. The rate of successful procedures and the ECG features were analyzed and compared between the two groups. Results. The highest success rate was found in patients with VPCs from the right ventricular outflow tract (RVOT), and the lowest success rate was evident among patients with complexes from both the RVOT and the left ventricular OT (LVOT). The patients with successful procedures (136) reflected a lower pseudo delta wave ratio (16.2% vs. 44.4%, P<0.01), a smaller R-wave amplitude in lead V1 (V1) (0.23±0.24 mV vs. 0.35±0.44 mV, P<0.05), shorter intrinsicoid deflection time in lead V2 (V2) (44.00±18.33 ms vs. 57.41±20.67 ms, P<0.01), a shorter RS duration in V2 (93.67±21.33 ms vs. 106.93±18.76 ms, P<0.01), and smaller R/S-waveratios in V2. Furthermore, multivariate analysis demonstrated that RS duration in V2 was above 109.17 ms and R/S ratio in V2 was above 0.28, forecasting a failed procedure. Conclusions. The ECG predictors of failed ablation were characterized by RS duration and R/S ratio in V2.http://dx.doi.org/10.1155/2022/8160144
spellingShingle Zhen Ye
Zhe Xu
Kezeng Gong
Xuehai Chen
Weiwei Wang
Jianhua Chen
Lianglong Chen
Feilong Zhang
Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
Cardiovascular Therapeutics
title Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
title_full Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
title_fullStr Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
title_full_unstemmed Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
title_short Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes
title_sort electrocardiogram parameters that affect the success rate of radiofrequency ablation in patients with outflow tract ventricular premature complexes
url http://dx.doi.org/10.1155/2022/8160144
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