Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon

Angioedema can cause potentially life-threatening airway obstruction. This case report describes an exceedingly rare episode of ticagrelor-induced hypersensitivity reaction, manifesting as angioedema with periorbital and likely respiratory involvement. The heart team should be vigilant for this prec...

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Main Authors: Rajeev Seecheran, Valmiki Seecheran, Sangeeta Persad, Sasha Lalla, Naveen Anand Seecheran
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2017/7612713
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author Rajeev Seecheran
Valmiki Seecheran
Sangeeta Persad
Sasha Lalla
Naveen Anand Seecheran
author_facet Rajeev Seecheran
Valmiki Seecheran
Sangeeta Persad
Sasha Lalla
Naveen Anand Seecheran
author_sort Rajeev Seecheran
collection DOAJ
description Angioedema can cause potentially life-threatening airway obstruction. This case report describes an exceedingly rare episode of ticagrelor-induced hypersensitivity reaction, manifesting as angioedema with periorbital and likely respiratory involvement. The heart team should be vigilant for this precarious condition which may require emergent airway management. Desensitization protocols and alternative regimens (e.g., clopidogrel, prasugrel, and addition of an adjunctive anticoagulant) should be considered when there is an absolute indication for antiplatelet therapy.
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id doaj-art-ea10f0e0db5d472aa73e75df842875f9
institution Kabale University
issn 2090-6404
2090-6412
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-ea10f0e0db5d472aa73e75df842875f92025-02-03T01:13:11ZengWileyCase Reports in Cardiology2090-64042090-64122017-01-01201710.1155/2017/76127137612713Ticagrelor-Induced Angioedema: A Rare and Unexpected PhenomenonRajeev Seecheran0Valmiki Seecheran1Sangeeta Persad2Sasha Lalla3Naveen Anand Seecheran4University of the West Indies, St. Augustine, Trinidad and TobagoNorth West Regional Health Authority, Mt. Hope, Trinidad and TobagoNorth West Regional Health Authority, Mt. Hope, Trinidad and TobagoAdvanced Cardiovascular Institute, Port of Spain, Trinidad and TobagoUniversity of the West Indies, St. Augustine, Trinidad and TobagoAngioedema can cause potentially life-threatening airway obstruction. This case report describes an exceedingly rare episode of ticagrelor-induced hypersensitivity reaction, manifesting as angioedema with periorbital and likely respiratory involvement. The heart team should be vigilant for this precarious condition which may require emergent airway management. Desensitization protocols and alternative regimens (e.g., clopidogrel, prasugrel, and addition of an adjunctive anticoagulant) should be considered when there is an absolute indication for antiplatelet therapy.http://dx.doi.org/10.1155/2017/7612713
spellingShingle Rajeev Seecheran
Valmiki Seecheran
Sangeeta Persad
Sasha Lalla
Naveen Anand Seecheran
Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
Case Reports in Cardiology
title Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
title_full Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
title_fullStr Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
title_full_unstemmed Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
title_short Ticagrelor-Induced Angioedema: A Rare and Unexpected Phenomenon
title_sort ticagrelor induced angioedema a rare and unexpected phenomenon
url http://dx.doi.org/10.1155/2017/7612713
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