Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate

Strong immune responses and robust protection following a novel protein in adjuvant tuberculosis vaccine candidate

Abstract BCG remains the only licensed vaccine for tuberculosis (TB), but its efficacy wanes over time. Subunit vaccines, aim to improve BCG immunity and protection, by inducing responses to a few mycobacterial antigens delivered with a specific platform. Since the platform shapes the immune respons...

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Bibliographic Details
Main Authors: Marcellus Korompis, Christopher J De Voss, Shuailin Li, Alexandre Richard, Salem Salman Almujri, Alberta Ateere, Géraldine Frank, Céline Lemoine, Helen McShane, Elena Stylianou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Tuberculosis
Vaccine
Heterologous
Viral vector
Adjuvants
Protection
Online Access:https://doi.org/10.1038/s41598-024-84667-8
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