Tendon Regeneration and Repair with Stem Cells

The use of stems cells in tendon repair is of particular interest given the frequency of tendon injuries worldwide together with the technical difficulty often encountered when repairing or augmenting tendons. Stems cells have the capability to differentiate into a variety of different cell types i...

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Main Authors: S. MacLean, W. S. Khan, A. A. Malik, M. Snow, S. Anand
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2012/316281
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author S. MacLean
W. S. Khan
A. A. Malik
M. Snow
S. Anand
author_facet S. MacLean
W. S. Khan
A. A. Malik
M. Snow
S. Anand
author_sort S. MacLean
collection DOAJ
description The use of stems cells in tendon repair is of particular interest given the frequency of tendon injuries worldwide together with the technical difficulty often encountered when repairing or augmenting tendons. Stems cells have the capability to differentiate into a variety of different cell types including osteocytes and tenocytes, and if normal architecture of damaged tendon (either macroscopic or microscopic) could be restored, this would significantly improve the management of patients with these injuries. There is already encouraging research on the use of stems cells clinically although considerable further work is required to improve knowledge and clinical applications of stem cells in tissue engineering.
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id doaj-art-e9e3e944cce344f4b5ef30fccaa45c3a
institution Kabale University
issn 1687-966X
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language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Stem Cells International
spelling doaj-art-e9e3e944cce344f4b5ef30fccaa45c3a2025-02-03T01:12:56ZengWileyStem Cells International1687-966X1687-96782012-01-01201210.1155/2012/316281316281Tendon Regeneration and Repair with Stem CellsS. MacLean0W. S. Khan1A. A. Malik2M. Snow3S. Anand4University of Manchester, Manchester M13 9PL, UKRoyal National Orthopaedic Hospital, Middlesex HA7 4LP, UKRoyal National Orthopaedic Hospital, Middlesex HA7 4LP, UKRoyal Orthopaedic Hospital, Birmingham B31 2AP, UKUniversity of Manchester, Manchester M13 9PL, UKThe use of stems cells in tendon repair is of particular interest given the frequency of tendon injuries worldwide together with the technical difficulty often encountered when repairing or augmenting tendons. Stems cells have the capability to differentiate into a variety of different cell types including osteocytes and tenocytes, and if normal architecture of damaged tendon (either macroscopic or microscopic) could be restored, this would significantly improve the management of patients with these injuries. There is already encouraging research on the use of stems cells clinically although considerable further work is required to improve knowledge and clinical applications of stem cells in tissue engineering.http://dx.doi.org/10.1155/2012/316281
spellingShingle S. MacLean
W. S. Khan
A. A. Malik
M. Snow
S. Anand
Tendon Regeneration and Repair with Stem Cells
Stem Cells International
title Tendon Regeneration and Repair with Stem Cells
title_full Tendon Regeneration and Repair with Stem Cells
title_fullStr Tendon Regeneration and Repair with Stem Cells
title_full_unstemmed Tendon Regeneration and Repair with Stem Cells
title_short Tendon Regeneration and Repair with Stem Cells
title_sort tendon regeneration and repair with stem cells
url http://dx.doi.org/10.1155/2012/316281
work_keys_str_mv AT smaclean tendonregenerationandrepairwithstemcells
AT wskhan tendonregenerationandrepairwithstemcells
AT aamalik tendonregenerationandrepairwithstemcells
AT msnow tendonregenerationandrepairwithstemcells
AT sanand tendonregenerationandrepairwithstemcells