Multifunctional astragalus polysaccharide composited microneedle promotes oral ulcers healing by inhibiting ferroptosis via Nrf2/HO-1/SLC7A11 axis

Multifunctional astragalus polysaccharide composited microneedle promotes oral ulcers healing by inhibiting ferroptosis via Nrf2/HO-1/SLC7A11 axis

Oral ulcers, a prevalent mucosal disorder with high recurrence rates, remain challenging to treat due to the oral cavity's dynamic environment and the multifactorial nature of ulcer progression. Here, we report a multifunctional microneedle (MN) patch loaded with astragalus polysaccharide (APS-...

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Bibliographic Details
Main Authors: Qiang Zhang, Tuo Wang, Junyu Ren, Yanru Guo, Ziyi Yin, Chenrui Zhang, Honglin Fan, Yinting Ren, Junlong Da, Narisu Hu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Oral ulcers
Astragalus polysaccharide
Microneedle
ROS
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425004338
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