Blocking CCL3-mediated neutrophil recruitment into the brain alleviates immunopathology following severe enterovirus 71 infection

Blocking CCL3-mediated neutrophil recruitment into the brain alleviates immunopathology following severe enterovirus 71 infection

Summary: Inflammatory cells infiltration in the cerebrospinal fluid is a hallmark of severe enterovirus 71 (EV71) infection, but which type of immune cells are critical for severe EV71 infection remains unclear. Here, we observe that both neutrophils and macrophages are increased in the brains of pa...

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Bibliographic Details
Main Authors: Wenxian Yang, Li Li, Guanlin Li, Xiuhui Li, Hongyan Liu, Xuelian Han, Yuan Wang, Yali Sun, Yuwei Wei, Bo Gao, Guangyu Zhao, Lei Sun, Min Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Immunology
Clinical neuroscience
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026130
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