Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

The development of new anticancer treatments, their clinical evaluation and introduction into the healthcare system need improvement. New drugs and cell therapies often come with significant costs for society while only marginally improving patients' survival and health‐related quality‐of‐life....

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Main Authors: Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.70058
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author Anton Berns
Ulrik Ringborg
Julio Celis
Bengt Jönsson
Michael Baumann
author_facet Anton Berns
Ulrik Ringborg
Julio Celis
Bengt Jönsson
Michael Baumann
author_sort Anton Berns
collection DOAJ
description The development of new anticancer treatments, their clinical evaluation and introduction into the healthcare system need improvement. New drugs and cell therapies often come with significant costs for society while only marginally improving patients' survival and health‐related quality‐of‐life. Therefore, bold, innovative clinical trials with critical assessment of the efficacy and cost‐effectiveness of new preventive measures and medical treatments are needed to ensure that patients and society benefit. Drug development programmes controlled by pharma should be complemented with initiatives such as stop studies, dose reduction, combination and repurposing trials. These should be validated in academia‐initiated trials supported by societal funds. Special attention should be devoted to paediatric and rare adult cancers. Comprehensive Cancer Centres (CCCs) covering the entire cancer research continuum, present throughout the EU, are critical for this. More of such centres must be established concomitantly with a robust accreditation methodology to ensure that they meet appropriate quality standards. It is crucial that funding for these initiatives, now temporarily and partially provided by the EU Cancer Mission and Europe's Beating Cancer Plan, is secured for a much longer period.
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spelling doaj-art-e9aec9622c824b068d67d583ca4c9fae2025-08-20T03:25:33ZengWileyMolecular Oncology1574-78911878-02612025-06-011961553156010.1002/1878-0261.70058Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in EuropeAnton Berns0Ulrik Ringborg1Julio Celis2Bengt Jönsson3Michael Baumann4European Academy of Cancer Sciences Stockholm SwedenEuropean Academy of Cancer Sciences Stockholm SwedenEuropean Academy of Cancer Sciences Stockholm SwedenEuropean Academy of Cancer Sciences Stockholm SwedenEuropean Academy of Cancer Sciences Stockholm SwedenThe development of new anticancer treatments, their clinical evaluation and introduction into the healthcare system need improvement. New drugs and cell therapies often come with significant costs for society while only marginally improving patients' survival and health‐related quality‐of‐life. Therefore, bold, innovative clinical trials with critical assessment of the efficacy and cost‐effectiveness of new preventive measures and medical treatments are needed to ensure that patients and society benefit. Drug development programmes controlled by pharma should be complemented with initiatives such as stop studies, dose reduction, combination and repurposing trials. These should be validated in academia‐initiated trials supported by societal funds. Special attention should be devoted to paediatric and rare adult cancers. Comprehensive Cancer Centres (CCCs) covering the entire cancer research continuum, present throughout the EU, are critical for this. More of such centres must be established concomitantly with a robust accreditation methodology to ensure that they meet appropriate quality standards. It is crucial that funding for these initiatives, now temporarily and partially provided by the EU Cancer Mission and Europe's Beating Cancer Plan, is secured for a much longer period.https://doi.org/10.1002/1878-0261.70058affordabilitycomprehensive cancer centreEU Cancer Missionfundinghealth‐related quality of lifePI‐initiated clinical trials
spellingShingle Anton Berns
Ulrik Ringborg
Julio Celis
Bengt Jönsson
Michael Baumann
Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
Molecular Oncology
affordability
comprehensive cancer centre
EU Cancer Mission
funding
health‐related quality of life
PI‐initiated clinical trials
title Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
title_full Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
title_fullStr Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
title_full_unstemmed Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
title_short Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe
title_sort strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in europe
topic affordability
comprehensive cancer centre
EU Cancer Mission
funding
health‐related quality of life
PI‐initiated clinical trials
url https://doi.org/10.1002/1878-0261.70058
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AT bengtjonsson strategiestoreducethecancerburdenandimproveaccesstoeffectiveandaffordablecancerinterventionsineurope
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