A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy

This article reports an 8-year-old female patient who underwent trans-thoracic small-incision interventional Pm-VSD occlusion with an eccentric umbrella (defect diameter 10 mm, occluder waist diameter 12 mm) at 4 months of age (July 2017). Seven years after the operation (October 2024), she graduall...

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Main Authors: Lihui Wei, Decai Zeng, Liuliu Huang, Xiangjie Luo, Ji Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1591928/full
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author Lihui Wei
Decai Zeng
Liuliu Huang
Xiangjie Luo
Ji Wu
author_facet Lihui Wei
Decai Zeng
Liuliu Huang
Xiangjie Luo
Ji Wu
author_sort Lihui Wei
collection DOAJ
description This article reports an 8-year-old female patient who underwent trans-thoracic small-incision interventional Pm-VSD occlusion with an eccentric umbrella (defect diameter 10 mm, occluder waist diameter 12 mm) at 4 months of age (July 2017). Seven years after the operation (October 2024), she gradually developed third-degree atrioventricular block. Despite the removal of the occluder and ventricular septal defect repair combined with steroid pulse therapy, the conduction abnormality persisted. This case, with a 7 - year disease course evolution, provides in - depth insights into the development process of delayed complete atrioventricular block (CAVB) following eccentric umbrella occlusion in infancy and early childhood, particularly for high - risk patients with occlusion adjacent to the conduction system. It also suggests the significance of electrocardiogram monitoring for over 5 years post - operation in such high - risk patients.
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institution OA Journals
issn 2296-2360
language English
publishDate 2025-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pediatrics
spelling doaj-art-e99e8ea02a93463e83932fbcf525f8d42025-08-20T02:31:48ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-06-011310.3389/fped.2025.15919281591928A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancyLihui Wei0Decai Zeng1Liuliu Huang2Xiangjie Luo3Ji Wu4Department of Ultrasonic Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Ultrasonic Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaDepartment of Ultrasonic Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, ChinaThis article reports an 8-year-old female patient who underwent trans-thoracic small-incision interventional Pm-VSD occlusion with an eccentric umbrella (defect diameter 10 mm, occluder waist diameter 12 mm) at 4 months of age (July 2017). Seven years after the operation (October 2024), she gradually developed third-degree atrioventricular block. Despite the removal of the occluder and ventricular septal defect repair combined with steroid pulse therapy, the conduction abnormality persisted. This case, with a 7 - year disease course evolution, provides in - depth insights into the development process of delayed complete atrioventricular block (CAVB) following eccentric umbrella occlusion in infancy and early childhood, particularly for high - risk patients with occlusion adjacent to the conduction system. It also suggests the significance of electrocardiogram monitoring for over 5 years post - operation in such high - risk patients.https://www.frontiersin.org/articles/10.3389/fped.2025.1591928/fullperimembranous ventricular septal defecttrans-thoracic occlusioneccentric occluderdelayed atrioventricular blockdevice-related complications
spellingShingle Lihui Wei
Decai Zeng
Liuliu Huang
Xiangjie Luo
Ji Wu
A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
Frontiers in Pediatrics
perimembranous ventricular septal defect
trans-thoracic occlusion
eccentric occluder
delayed atrioventricular block
device-related complications
title A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
title_full A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
title_fullStr A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
title_full_unstemmed A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
title_short A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
title_sort case report of delayed persistent third degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy
topic perimembranous ventricular septal defect
trans-thoracic occlusion
eccentric occluder
delayed atrioventricular block
device-related complications
url https://www.frontiersin.org/articles/10.3389/fped.2025.1591928/full
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