National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022

Abstract Dyslipidemia has steadily increased in South Korea over the past two decades, emerging as a major public health concern and key risk factor for cardiovascular disease. Thus, our study aimed to investigate long-term trends in the prevalence, awareness, treatment, and control of dyslipidemia...

Full description

Saved in:
Bibliographic Details
Main Authors: Hyeseung Lee, Seokjun Kim, Yejun Son, Soeun Kim, Hyeon Jin Kim, Hyesu Jo, Jaeyu Park, Kyeongmin Lee, Hayeon Lee, Jiseung Kang, Selin Woo, Sunyoung Kim, Sang Youl Rhee, Jiyoung Hwang, Lee Smith, Dong Keon Yon
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-00354-2
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849766924761694208
author Hyeseung Lee
Seokjun Kim
Yejun Son
Soeun Kim
Hyeon Jin Kim
Hyesu Jo
Jaeyu Park
Kyeongmin Lee
Hayeon Lee
Jiseung Kang
Selin Woo
Sunyoung Kim
Sang Youl Rhee
Jiyoung Hwang
Lee Smith
Dong Keon Yon
author_facet Hyeseung Lee
Seokjun Kim
Yejun Son
Soeun Kim
Hyeon Jin Kim
Hyesu Jo
Jaeyu Park
Kyeongmin Lee
Hayeon Lee
Jiseung Kang
Selin Woo
Sunyoung Kim
Sang Youl Rhee
Jiyoung Hwang
Lee Smith
Dong Keon Yon
author_sort Hyeseung Lee
collection DOAJ
description Abstract Dyslipidemia has steadily increased in South Korea over the past two decades, emerging as a major public health concern and key risk factor for cardiovascular disease. Thus, our study aimed to investigate long-term trends in the prevalence, awareness, treatment, and control of dyslipidemia in South Korea, including the COVID-19 pandemic. This study utilized data from nationally representative cross-sectional surveys conducted as part of the Korea National Health and Nutrition Examination Survey from 2005 to 2022, analyzing long-term trends of dyslipidemia among 98,396 individuals aged over 30. Weighted linear and binary logistic regression were performed to calculate the β coefficients, βdiff, and weighted odds ratios with 95% confidence intervals (CIs). Weighted odds ratios were computed for various socioeconomic groups using aggregated data from 2005 to 2022. The prevalence of dyslipidemia increased from 41.30% (95% CI 40.40–42.21) in 2005–2009 to 48.41% (47.36–49.47) in 2020–2022. Awareness increased from 17.87% (16.75–18.99) to 48.90% (47.34–50.47), treatment from 7.10% (6.39–7.80) to 38.19% (36.61–39.76), and control among prevalence from 6.49% (5.79–7.19) to 31.82% (30.33–33.32). Treatment (βdiff, 3.94 [1.97–5.92]) and control among prevalence (βdiff, 3.52 [1.67–5.38]) increased more rapidly during the pandemic. Higher odds of dyslipidemia were associated with male sex, older population, rural residence, high BMI, central adiposity, low education and income levels, smoking, and high-risk alcohol consumption. Lower odds of awareness, treatment, and control among individuals with dyslipidemia were associated with male sex, younger population, rural residence, higher education and income levels, smoking, and high-risk alcohol consumption. Over the past 18 years, the prevalence, awareness, treatment, and control of dyslipidemia have steadily increased, with persistent disparities among socioeconomic groups.
format Article
id doaj-art-e992282dde324928b77f63ec00a87881
institution DOAJ
issn 2045-2322
language English
publishDate 2025-05-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-e992282dde324928b77f63ec00a878812025-08-20T03:04:25ZengNature PortfolioScientific Reports2045-23222025-05-0115111710.1038/s41598-025-00354-2National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022Hyeseung Lee0Seokjun Kim1Yejun Son2Soeun Kim3Hyeon Jin Kim4Hyesu Jo5Jaeyu Park6Kyeongmin Lee7Hayeon Lee8Jiseung Kang9Selin Woo10Sunyoung Kim11Sang Youl Rhee12Jiyoung Hwang13Lee Smith14Dong Keon Yon15Department of Medicine, Kyung Hee University College of MedicineDepartment of Medicine, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineCenter for Digital Health, Medical Science Research Institute, Kyung Hee University College of MedicineDivision of Sleep Medicine, Harvard Medical SchoolDepartment of Medicine, Kyung Hee University College of MedicineDepartment of Family Medicine, Kyung Hee University Medical Center, Kyung Hee University College of MedicineDepartment of Medicine, Kyung Hee University College of MedicineDepartment of Medicine, Kyung Hee University College of MedicineCentre for Health, Performance and Wellbeing, Anglia Ruskin UniversityDepartment of Medicine, Kyung Hee University College of MedicineAbstract Dyslipidemia has steadily increased in South Korea over the past two decades, emerging as a major public health concern and key risk factor for cardiovascular disease. Thus, our study aimed to investigate long-term trends in the prevalence, awareness, treatment, and control of dyslipidemia in South Korea, including the COVID-19 pandemic. This study utilized data from nationally representative cross-sectional surveys conducted as part of the Korea National Health and Nutrition Examination Survey from 2005 to 2022, analyzing long-term trends of dyslipidemia among 98,396 individuals aged over 30. Weighted linear and binary logistic regression were performed to calculate the β coefficients, βdiff, and weighted odds ratios with 95% confidence intervals (CIs). Weighted odds ratios were computed for various socioeconomic groups using aggregated data from 2005 to 2022. The prevalence of dyslipidemia increased from 41.30% (95% CI 40.40–42.21) in 2005–2009 to 48.41% (47.36–49.47) in 2020–2022. Awareness increased from 17.87% (16.75–18.99) to 48.90% (47.34–50.47), treatment from 7.10% (6.39–7.80) to 38.19% (36.61–39.76), and control among prevalence from 6.49% (5.79–7.19) to 31.82% (30.33–33.32). Treatment (βdiff, 3.94 [1.97–5.92]) and control among prevalence (βdiff, 3.52 [1.67–5.38]) increased more rapidly during the pandemic. Higher odds of dyslipidemia were associated with male sex, older population, rural residence, high BMI, central adiposity, low education and income levels, smoking, and high-risk alcohol consumption. Lower odds of awareness, treatment, and control among individuals with dyslipidemia were associated with male sex, younger population, rural residence, higher education and income levels, smoking, and high-risk alcohol consumption. Over the past 18 years, the prevalence, awareness, treatment, and control of dyslipidemia have steadily increased, with persistent disparities among socioeconomic groups.https://doi.org/10.1038/s41598-025-00354-2COVID-19PandemicDyslipidemiaPrevalenceSouth KoreaTrend
spellingShingle Hyeseung Lee
Seokjun Kim
Yejun Son
Soeun Kim
Hyeon Jin Kim
Hyesu Jo
Jaeyu Park
Kyeongmin Lee
Hayeon Lee
Jiseung Kang
Selin Woo
Sunyoung Kim
Sang Youl Rhee
Jiyoung Hwang
Lee Smith
Dong Keon Yon
National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
Scientific Reports
COVID-19
Pandemic
Dyslipidemia
Prevalence
South Korea
Trend
title National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
title_full National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
title_fullStr National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
title_full_unstemmed National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
title_short National trends in dyslipidemia prevalence, awareness, treatment, and control in South Korea from 2005 to 2022
title_sort national trends in dyslipidemia prevalence awareness treatment and control in south korea from 2005 to 2022
topic COVID-19
Pandemic
Dyslipidemia
Prevalence
South Korea
Trend
url https://doi.org/10.1038/s41598-025-00354-2
work_keys_str_mv AT hyeseunglee nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT seokjunkim nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT yejunson nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT soeunkim nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT hyeonjinkim nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT hyesujo nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT jaeyupark nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT kyeongminlee nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT hayeonlee nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT jiseungkang nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT selinwoo nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT sunyoungkim nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT sangyoulrhee nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT jiyounghwang nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT leesmith nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022
AT dongkeonyon nationaltrendsindyslipidemiaprevalenceawarenesstreatmentandcontrolinsouthkoreafrom2005to2022