The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
Despite the discovery of 5 alpha-reduction as an enzymatic step in steroid metabolism in 1951, and the discovery that dihydrotestosterone is more potent than testosterone in 1968, the significance of 5 alpha-reduced steroids in human diseases was not appreciated until the discovery of 5 alpha-reduct...
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Main Authors: | Faris Azzouni, Alejandro Godoy, Yun Li, James Mohler |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Advances in Urology |
Online Access: | http://dx.doi.org/10.1155/2012/530121 |
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