The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases

Despite the discovery of 5 alpha-reduction as an enzymatic step in steroid metabolism in 1951, and the discovery that dihydrotestosterone is more potent than testosterone in 1968, the significance of 5 alpha-reduced steroids in human diseases was not appreciated until the discovery of 5 alpha-reduct...

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Bibliographic Details
Main Authors: Faris Azzouni, Alejandro Godoy, Yun Li, James Mohler
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2012/530121
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