Microbiome Modulation in Pediatric Leukemia: Impact on Graft-Versus-Host Disease and Treatment Outcomes: A Narrative Review

Microbiome Modulation in Pediatric Leukemia: Impact on Graft-Versus-Host Disease and Treatment Outcomes: A Narrative Review

The gut microbiome significantly influences the outcomes of pediatric leukemia, particularly in patients undergoing hematopoietic stem cell transplantation (HSCT). Dysbiosis, caused by chemotherapy, antibiotics, and immune system changes, contributes to complications such as graft-versus-host diseas...

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Bibliographic Details
Main Authors: Samuel Bogdan Todor, Cristian Ichim
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Children
Subjects:
childhood leukemia
gut microbiome
fecal microbiota transplant
hematopoietic stem-cell transplant
graft-versus-host disease
Online Access:https://www.mdpi.com/2227-9067/12/2/166
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