ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS
We studied capabilities of the Bruker Microflex MALDI-TOF device for species identification of anaerobic gramnegative cocci isolated from clinical specimens of cancer patients. Seventy clinical isolates of Veillonella spp. and one Acidaminococcus spp were analyzed. All isolates were identified to th...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Russian Academy of Sciences, Tomsk National Research Medical Center
2018-03-01
|
| Series: | Сибирский онкологический журнал |
| Subjects: | |
| Online Access: | https://www.siboncoj.ru/jour/article/view/665 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850030548775337984 |
|---|---|
| author | I. V. Tereshchenko Z. V. Grigorievskaya I. N. Petukhova I. I. Shilnikova Е. D. Grigorievsky О. V. Tereshchenko V. V. Aginova N. V. Dmitrieva |
| author_facet | I. V. Tereshchenko Z. V. Grigorievskaya I. N. Petukhova I. I. Shilnikova Е. D. Grigorievsky О. V. Tereshchenko V. V. Aginova N. V. Dmitrieva |
| author_sort | I. V. Tereshchenko |
| collection | DOAJ |
| description | We studied capabilities of the Bruker Microflex MALDI-TOF device for species identification of anaerobic gramnegative cocci isolated from clinical specimens of cancer patients. Seventy clinical isolates of Veillonella spp. and one Acidaminococcus spp were analyzed. All isolates were identified to the species level with a scores greater than 1.9. The most common species were V. parvula (37 strains), followed by V. dispar (16), V. atypical (16) and V. denticariosi (1). Susceptibilities of the isolates were determined by the E-test methodology. All Veillonella isolates were susceptible to imipenem, whereas high resistance rates were observed for penicillin G, amoxicillin/clavulanate and metronidazole. The proportion of resistant isolates of V. parvula, V. dispar and V. atypica to penicillin was 86 %, 85 % and 100 %, respectively. The resistance to amoxicillin/clavulanate was observed in 28.6 % of V. parvula isolates, 23.1 % of V. dispar isolates and in 6.7 % of V. atypica isolates. Resistance to metronidazole (MIC ≥ 8 µg/ml) of V. parvula, V. dispar and V. atypica was 88.6 %, 53.8 % and 40 %, respectively. |
| format | Article |
| id | doaj-art-e97eed033b554d20a99404b34c19ed5d |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2018-03-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-e97eed033b554d20a99404b34c19ed5d2025-08-20T02:59:11ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682018-03-01171111810.21294/1814-4861-2018-17-1-11-18510ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTSI. V. Tereshchenko0Z. V. Grigorievskaya1I. N. Petukhova2I. I. Shilnikova3Е. D. Grigorievsky4О. V. Tereshchenko5V. V. Aginova6N. V. Dmitrieva7N.N. Blokhin National Medical Research Cancer CenterN.N. Blokhin National Medical Research Cancer CenterN.N. Blokhin National Medical Research Cancer CenterN.N. Blokhin National Medical Research Cancer CenterI.M. Sechenov First Moscow State Medical UniversityN.I. Pirogov Russian National Research Medical UniversityN.N. Blokhin National Medical Research Cancer Center; Medical college № 1N.N. Blokhin National Medical Research Cancer CenterWe studied capabilities of the Bruker Microflex MALDI-TOF device for species identification of anaerobic gramnegative cocci isolated from clinical specimens of cancer patients. Seventy clinical isolates of Veillonella spp. and one Acidaminococcus spp were analyzed. All isolates were identified to the species level with a scores greater than 1.9. The most common species were V. parvula (37 strains), followed by V. dispar (16), V. atypical (16) and V. denticariosi (1). Susceptibilities of the isolates were determined by the E-test methodology. All Veillonella isolates were susceptible to imipenem, whereas high resistance rates were observed for penicillin G, amoxicillin/clavulanate and metronidazole. The proportion of resistant isolates of V. parvula, V. dispar and V. atypica to penicillin was 86 %, 85 % and 100 %, respectively. The resistance to amoxicillin/clavulanate was observed in 28.6 % of V. parvula isolates, 23.1 % of V. dispar isolates and in 6.7 % of V. atypica isolates. Resistance to metronidazole (MIC ≥ 8 µg/ml) of V. parvula, V. dispar and V. atypica was 88.6 %, 53.8 % and 40 %, respectively.https://www.siboncoj.ru/jour/article/view/665veillonella clinical isolatesanaerobic infectionsmaldi-tof msantimicrobial susceptibilitycancer patients |
| spellingShingle | I. V. Tereshchenko Z. V. Grigorievskaya I. N. Petukhova I. I. Shilnikova Е. D. Grigorievsky О. V. Tereshchenko V. V. Aginova N. V. Dmitrieva ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS Сибирский онкологический журнал veillonella clinical isolates anaerobic infections maldi-tof ms antimicrobial susceptibility cancer patients |
| title | ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS |
| title_full | ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS |
| title_fullStr | ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS |
| title_full_unstemmed | ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS |
| title_short | ROLE OF GRAM-NEGATIVE ANAEROBIC COCCI BELONGING TO THE GENUS VEILLONELLA IN INFECTIOUS COMPLICATIONS IN CANCER PATIENTS |
| title_sort | role of gram negative anaerobic cocci belonging to the genus veillonella in infectious complications in cancer patients |
| topic | veillonella clinical isolates anaerobic infections maldi-tof ms antimicrobial susceptibility cancer patients |
| url | https://www.siboncoj.ru/jour/article/view/665 |
| work_keys_str_mv | AT ivtereshchenko roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT zvgrigorievskaya roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT inpetukhova roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT iishilnikova roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT edgrigorievsky roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT ovtereshchenko roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT vvaginova roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients AT nvdmitrieva roleofgramnegativeanaerobiccoccibelongingtothegenusveillonellaininfectiouscomplicationsincancerpatients |