Bladder p75<sup>NTR</sup>-Mediated Anti-Inflammatory Response via the TLR4/TRAF6/NF-κB Axis

Bladder p75<sup>NTR</sup>-Mediated Anti-Inflammatory Response via the TLR4/TRAF6/NF-κB Axis

Recurrent bacterial cystitis in women can lead to interstitial cystitis or bladder pain syndrome (IC/BPS). Activation of Toll-like receptor 4 (TLR4) by LPS can upregulate signaling of the pro-inflammatory receptor p75<sup>NTR</sup>. The aim of the presented study was to assess whether p7...

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Bibliographic Details
Main Authors: Claudia Covarrubias, Abubakr H. Mossa, Laura R. Yan, Benjamin Desormeau, Philippe G. Cammisotto, H. Uri Saragovi, Lysanne Campeau
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Life
Subjects:
p75<sup>NTR</sup>
THX-B antagonist
LPS
inflammatory pathways
bladder
Online Access:https://www.mdpi.com/2075-1729/15/6/957
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