Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review
This review delves into the emerging field of cerebellar Transcranial Magnetic Stimulation (TMS) in the rehabilitation of limb dysfunction following a stroke. It synthesizes findings from randomized controlled trials and case studies, examining the efficacy, safety, and underlying mechanisms of cere...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1405637/full |
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| author | Zhan Wang Likai Wang Likai Wang Fei Gao Yongli Dai Chunqiao Liu Jingyi Wu Mengchun Wang Qinjie Yan Yaning Chen Chengbin Wang Litong Wang |
| author_facet | Zhan Wang Likai Wang Likai Wang Fei Gao Yongli Dai Chunqiao Liu Jingyi Wu Mengchun Wang Qinjie Yan Yaning Chen Chengbin Wang Litong Wang |
| author_sort | Zhan Wang |
| collection | DOAJ |
| description | This review delves into the emerging field of cerebellar Transcranial Magnetic Stimulation (TMS) in the rehabilitation of limb dysfunction following a stroke. It synthesizes findings from randomized controlled trials and case studies, examining the efficacy, safety, and underlying mechanisms of cerebellar TMS. The review outlines advancements in TMS technologies, such as low-frequency repetitive TMS, intermittent Theta Burst Stimulation, and Cerebello-Motor Paired Associative Stimulation, and their integration with physiotherapy. The role of the cerebellum in motor control, the theoretical underpinnings of cerebellar stimulation on motor cortex excitability, and the indirect effects on cognition and motor learning are explored. Additionally, the review discusses current challenges, including coil types, safety, and optimal timing and modes of stimulation, and suggests future research directions. This comprehensive analysis highlights cerebellar TMS as a promising, though complex, approach in stroke rehabilitation, offering insights for its clinical optimization. |
| format | Article |
| id | doaj-art-e96d640ff61e4270a713d37edc7d9bda |
| institution | Kabale University |
| issn | 1662-453X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj-art-e96d640ff61e4270a713d37edc7d9bda2025-02-03T06:33:39ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2025-02-011910.3389/fnins.2025.14056371405637Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative reviewZhan Wang0Likai Wang1Likai Wang2Fei Gao3Yongli Dai4Chunqiao Liu5Jingyi Wu6Mengchun Wang7Qinjie Yan8Yaning Chen9Chengbin Wang10Litong Wang11Rehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, ChinaRehabilitation Center, Qilu Hospital of Shandong University, Jinan, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaDepartment of Neurology, Dalian Municipal Central Hospital, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaRehabilitation Medicine Department, The Second Hospital of Dalian Medical University, Dalian, ChinaThis review delves into the emerging field of cerebellar Transcranial Magnetic Stimulation (TMS) in the rehabilitation of limb dysfunction following a stroke. It synthesizes findings from randomized controlled trials and case studies, examining the efficacy, safety, and underlying mechanisms of cerebellar TMS. The review outlines advancements in TMS technologies, such as low-frequency repetitive TMS, intermittent Theta Burst Stimulation, and Cerebello-Motor Paired Associative Stimulation, and their integration with physiotherapy. The role of the cerebellum in motor control, the theoretical underpinnings of cerebellar stimulation on motor cortex excitability, and the indirect effects on cognition and motor learning are explored. Additionally, the review discusses current challenges, including coil types, safety, and optimal timing and modes of stimulation, and suggests future research directions. This comprehensive analysis highlights cerebellar TMS as a promising, though complex, approach in stroke rehabilitation, offering insights for its clinical optimization.https://www.frontiersin.org/articles/10.3389/fnins.2025.1405637/fullcerebellar transcranial magnetic stimulationstroke rehabilitationlimb dysfunctionneuroplasticitymotor recovery |
| spellingShingle | Zhan Wang Likai Wang Likai Wang Fei Gao Yongli Dai Chunqiao Liu Jingyi Wu Mengchun Wang Qinjie Yan Yaning Chen Chengbin Wang Litong Wang Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review Frontiers in Neuroscience cerebellar transcranial magnetic stimulation stroke rehabilitation limb dysfunction neuroplasticity motor recovery |
| title | Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review |
| title_full | Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review |
| title_fullStr | Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review |
| title_full_unstemmed | Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review |
| title_short | Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review |
| title_sort | exploring cerebellar transcranial magnetic stimulation in post stroke limb dysfunction rehabilitation a narrative review |
| topic | cerebellar transcranial magnetic stimulation stroke rehabilitation limb dysfunction neuroplasticity motor recovery |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2025.1405637/full |
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