Preclinical comparison of prolgolimab, pembrolizumab and nivolumab
Abstract Prolgolimab is a recombinant IgG1-based anti-PD-1 antibody, whose properties were improved by the introduction of the LALA mutation, and which has demonstrated high efficacy in patients with metastatic melanoma. This paper presents the results of comparative preclinical studies of antigen-b...
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| Main Authors: | Aleksandr Gordeev, Andrei Vaal, Maria Puchkova, Iana Smirnova, Aleksandr Doronin, Anna Znobishcheva, Daria Zhmudanova, Aleksei Aleksandrov, Mikhail Sukchev, Evgeny Imyanitov, Valery Solovyev, Pavel Iakovlev |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-72118-3 |
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