Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring

Hypercapnic respiratory failure arises due to an imbalance in the load-capacity-drive relationship of the respiratory muscle pump, typically arising in patients with chronic obstructive pulmonary disease, obesity-related respiratory failure, and neuromuscular disease. Patients at risk of developing...

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Main Authors: Laura Tregidgo, Prasheena Naran, Eshrina Gosal, Rebecca F. D’Cruz
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2024/7013576
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author Laura Tregidgo
Prasheena Naran
Eshrina Gosal
Rebecca F. D’Cruz
author_facet Laura Tregidgo
Prasheena Naran
Eshrina Gosal
Rebecca F. D’Cruz
author_sort Laura Tregidgo
collection DOAJ
description Hypercapnic respiratory failure arises due to an imbalance in the load-capacity-drive relationship of the respiratory muscle pump, typically arising in patients with chronic obstructive pulmonary disease, obesity-related respiratory failure, and neuromuscular disease. Patients at risk of developing chronic respiratory failure and those with established disease should be referred to a specialist ventilation unit for evaluation and consideration of home noninvasive ventilation (NIV) initiation. Clinical trials demonstrate that, following careful patient selection, home NIV can improve a range of clinical, patient-reported, and physiological outcomes. This narrative review provides an overview of the pathophysiology of chronic respiratory failure, evidence-based applications of home NIV, and monitoring of patients established on home ventilation and describes technological advances in ventilation devices, interfaces, and monitoring to enhance comfort, promote long-term adherence, and optimise gas exchange.
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spelling doaj-art-e9404a8070fe47e48a7dcb84f9604abf2025-02-03T07:23:45ZengWileyCanadian Respiratory Journal1916-72452024-01-01202410.1155/2024/7013576Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and MonitoringLaura Tregidgo0Prasheena Naran1Eshrina Gosal2Rebecca F. D’Cruz3Lane Fox Respiratory UnitDepartment of Respiratory MedicineDepartment of Respiratory MedicineLane Fox Respiratory UnitHypercapnic respiratory failure arises due to an imbalance in the load-capacity-drive relationship of the respiratory muscle pump, typically arising in patients with chronic obstructive pulmonary disease, obesity-related respiratory failure, and neuromuscular disease. Patients at risk of developing chronic respiratory failure and those with established disease should be referred to a specialist ventilation unit for evaluation and consideration of home noninvasive ventilation (NIV) initiation. Clinical trials demonstrate that, following careful patient selection, home NIV can improve a range of clinical, patient-reported, and physiological outcomes. This narrative review provides an overview of the pathophysiology of chronic respiratory failure, evidence-based applications of home NIV, and monitoring of patients established on home ventilation and describes technological advances in ventilation devices, interfaces, and monitoring to enhance comfort, promote long-term adherence, and optimise gas exchange.http://dx.doi.org/10.1155/2024/7013576
spellingShingle Laura Tregidgo
Prasheena Naran
Eshrina Gosal
Rebecca F. D’Cruz
Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
Canadian Respiratory Journal
title Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
title_full Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
title_fullStr Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
title_full_unstemmed Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
title_short Update in Noninvasive Home Mechanical Ventilation: A Narrative Review of Indications, Outcomes, and Monitoring
title_sort update in noninvasive home mechanical ventilation a narrative review of indications outcomes and monitoring
url http://dx.doi.org/10.1155/2024/7013576
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