Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia

Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea...

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Main Authors: Samid M. Farooqui, Muhammad S. Khan, Laura Adhikari, Viral Doshi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/2017/8513702
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author Samid M. Farooqui
Muhammad S. Khan
Laura Adhikari
Viral Doshi
author_facet Samid M. Farooqui
Muhammad S. Khan
Laura Adhikari
Viral Doshi
author_sort Samid M. Farooqui
collection DOAJ
description Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT.
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spelling doaj-art-e9282302cae644cabbefcfd62aa037dd2025-02-03T06:12:33ZengWileyCase Reports in Pulmonology2090-68462090-68542017-01-01201710.1155/2017/85137028513702Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive PneumoniaSamid M. Farooqui0Muhammad S. Khan1Laura Adhikari2Viral Doshi3Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USAGranular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT.http://dx.doi.org/10.1155/2017/8513702
spellingShingle Samid M. Farooqui
Muhammad S. Khan
Laura Adhikari
Viral Doshi
Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
Case Reports in Pulmonology
title Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_full Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_fullStr Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_full_unstemmed Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_short Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_sort multifocal pulmonary granular cell tumor presenting with postobstructive pneumonia
url http://dx.doi.org/10.1155/2017/8513702
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