Reduced immune response to SARS-CoV-2 infection in the elderly after 6 months

Reduced immune response to SARS-CoV-2 infection in the elderly after 6 months

ObjectivesTo evaluate the immune persistence and cross-immune response of elderly individuals after Omicron BA.5 infections.MethodThe neutralizing antibodies against WT, BA.5, XBB.1 and EG.5 strains were analyzed. The T/B-cell subsets’ responses were tested through intracellular cytokine staining an...

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Bibliographic Details
Main Authors: Qin Luo, Qinqin Song, Yan Li, Kexin Zong, Ti Liu, Junming He, Guoyong Mei, Haijun Du, Zhiqiang Xia, Mi Liu, Juan Song, Chen Gao, Dong Xia, Guangyu Xue, Wenyan Tian, Yinli Qu, Zengqiang Kou, Zhongjun Dong, Jun Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
omicron BA.5
elderly
neutralizing antibody
adaptive immunity
T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596065/full
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