Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital
Respiratory tract infections (RTIs) are prevalent in India, affecting approximately 11.3% of the population. India leads globally in lung disease mortality, including chronic obstructive pulmonary disease and asthma, contributing significantly to disability-adjusted life years and mortality rates....
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PAGEPress Publications
2025-03-01
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| Series: | Monaldi Archives for Chest Disease |
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| Online Access: | https://www.monaldi-archives.org/macd/article/view/3337 |
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| author | Chandrashekhar Mallikarjun Patil Princy Domnic Dsouza Sai Phalguna Prakash Chitralu Vinod Ashok Koujalagi Agadi Hiremath Viswanatha Swamy Sanatkumar Bharamu Nyamagoud |
| author_facet | Chandrashekhar Mallikarjun Patil Princy Domnic Dsouza Sai Phalguna Prakash Chitralu Vinod Ashok Koujalagi Agadi Hiremath Viswanatha Swamy Sanatkumar Bharamu Nyamagoud |
| author_sort | Chandrashekhar Mallikarjun Patil |
| collection | DOAJ |
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Respiratory tract infections (RTIs) are prevalent in India, affecting approximately 11.3% of the population. India leads globally in lung disease mortality, including chronic obstructive pulmonary disease and asthma, contributing significantly to disability-adjusted life years and mortality rates. The role of clinical pharmacist interventions (CPIs) in optimizing antibiotic use and managing RTIs is increasingly recognized as vital for improving patient outcomes and reducing healthcare costs. This study aimed to evaluate the effectiveness of CPIs in managing RTIs among inpatients at Vivekananda General Hospital, Hubballi, and to identify common drug-related problems (DRPs) using the Hepler-Strand classification system. A cross-sectional study was conducted over 6 months, including 200 inpatients diagnosed with RTIs. Data was collected through patient profiles, treatment charts, and medical case sheets. The study employed descriptive and inferential statistical analyses to evaluate the impact of CPIs on antibiotic therapy and the prevalence of DRPs. The study identified drug-drug interactions as the most frequent DRP (38.30%), followed by drug duplication (31.49%) and improper drug selection (9.79%). Other issues included adverse drug reactions (4.68%), overdosage (5.53%), untreated indications (6.38%), subtherapeutic dosage (2.13%), and drug use without indication (1.70%). CPIs, including prospective audits, prescription feedback, and healthcare professional education, effectively addressed these issues, improved antibiotic appropriateness, and optimized patient outcomes. CPIs significantly enhance the management of RTIs by addressing various DRPs and optimizing antibiotic use. The study underscores the importance of incorporating pharmacists into antimicrobial stewardship programs to improve medication safety, efficacy, and overall patient care in managing RTIs. Continued emphasis on pharmacist-led interventions and adherence to best practices in antimicrobial stewardship is essential for reducing the burden of respiratory diseases in India.
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| format | Article |
| id | doaj-art-e9138fc9c3be4e2f8eca5b970427a0df |
| institution | DOAJ |
| issn | 1122-0643 2532-5264 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | PAGEPress Publications |
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| series | Monaldi Archives for Chest Disease |
| spelling | doaj-art-e9138fc9c3be4e2f8eca5b970427a0df2025-08-20T02:41:10ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642025-03-0110.4081/monaldi.2025.3337Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospitalChandrashekhar Mallikarjun Patil0Princy Domnic Dsouza1https://orcid.org/0009-0004-5440-3259Sai Phalguna Prakash Chitralu2Vinod Ashok Koujalagi3Agadi Hiremath Viswanatha Swamy4Sanatkumar Bharamu Nyamagoud5https://orcid.org/0000-0002-5111-7685Department of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, KarnatakaDepartment of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, KarnatakaDepartment of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, KarnatakaDepartment of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, KarnatakaDepartment of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, KarnatakaDepartment of Pharmacy Practice, KLE College of Pharmacy, Vidyanagar, Hubballi, Karnataka Respiratory tract infections (RTIs) are prevalent in India, affecting approximately 11.3% of the population. India leads globally in lung disease mortality, including chronic obstructive pulmonary disease and asthma, contributing significantly to disability-adjusted life years and mortality rates. The role of clinical pharmacist interventions (CPIs) in optimizing antibiotic use and managing RTIs is increasingly recognized as vital for improving patient outcomes and reducing healthcare costs. This study aimed to evaluate the effectiveness of CPIs in managing RTIs among inpatients at Vivekananda General Hospital, Hubballi, and to identify common drug-related problems (DRPs) using the Hepler-Strand classification system. A cross-sectional study was conducted over 6 months, including 200 inpatients diagnosed with RTIs. Data was collected through patient profiles, treatment charts, and medical case sheets. The study employed descriptive and inferential statistical analyses to evaluate the impact of CPIs on antibiotic therapy and the prevalence of DRPs. The study identified drug-drug interactions as the most frequent DRP (38.30%), followed by drug duplication (31.49%) and improper drug selection (9.79%). Other issues included adverse drug reactions (4.68%), overdosage (5.53%), untreated indications (6.38%), subtherapeutic dosage (2.13%), and drug use without indication (1.70%). CPIs, including prospective audits, prescription feedback, and healthcare professional education, effectively addressed these issues, improved antibiotic appropriateness, and optimized patient outcomes. CPIs significantly enhance the management of RTIs by addressing various DRPs and optimizing antibiotic use. The study underscores the importance of incorporating pharmacists into antimicrobial stewardship programs to improve medication safety, efficacy, and overall patient care in managing RTIs. Continued emphasis on pharmacist-led interventions and adherence to best practices in antimicrobial stewardship is essential for reducing the burden of respiratory diseases in India. https://www.monaldi-archives.org/macd/article/view/3337RTIchronic obstructive pulmonary disorderasthmaclinical pharmacist interventionantimicrobial stewardship programs |
| spellingShingle | Chandrashekhar Mallikarjun Patil Princy Domnic Dsouza Sai Phalguna Prakash Chitralu Vinod Ashok Koujalagi Agadi Hiremath Viswanatha Swamy Sanatkumar Bharamu Nyamagoud Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital Monaldi Archives for Chest Disease RTI chronic obstructive pulmonary disorder asthma clinical pharmacist intervention antimicrobial stewardship programs |
| title | Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| title_full | Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| title_fullStr | Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| title_full_unstemmed | Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| title_short | Optimizing respiratory care: clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| title_sort | optimizing respiratory care clinical pharmacist interventions in respiratory tract infection management at a tertiary teaching hospital |
| topic | RTI chronic obstructive pulmonary disorder asthma clinical pharmacist intervention antimicrobial stewardship programs |
| url | https://www.monaldi-archives.org/macd/article/view/3337 |
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