Cell Ratio-Dependent Osteoblast–Endothelial Cell Crosstalk Promoting Osteogenesis–Angiogenesis Coupling via Regulation of Microfluidic Perfusion and Paracrine Signaling

Osteogenesis–angiogenesis coupling, a dynamic and coordinated interaction between skeletal and vascular cells, is essential for fracture healing. However, the effects of these cell ratios and their interactions under microfluidic perfusion and paracrine signaling on osteogenesis–angiogenesis couplin...

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Bibliographic Details
Main Authors: Yuexin Wang, Shu Chen, Wenwen Fan, Sixian Zhang, Xi Chen
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Micromachines
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Online Access:https://www.mdpi.com/2072-666X/16/5/539
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