Biology and Biotechnology of Follicle Development
Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The preantral early antral follicle transition is the stage of follicular development durin...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/938138 |
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| _version_ | 1832558141477224448 |
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| author | Gustavo Adolfo Palma Martin Eduardo Argañaraz Antonio Daniel Barrera Daniela Rodler Adrian Ángel Mutto Fred Sinowatz |
| author_facet | Gustavo Adolfo Palma Martin Eduardo Argañaraz Antonio Daniel Barrera Daniela Rodler Adrian Ángel Mutto Fred Sinowatz |
| author_sort | Gustavo Adolfo Palma |
| collection | DOAJ |
| description | Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the progression into growing or atresia of the follicle is made. Follicular growth during this period is tightly regulated by oocyte-granulosatheca cell interactions. A cluster of early expressed genes is required for normal folliculogenesis. Granulosa cell factors stimulate the recruitment of theca cells from cortical stromal cells. Thecal factors promote granulosa cell proliferation and suppress granulosa cell apoptosis. Cell-cell and cell-extracellular matrix interactions influence the production of growth factors in the different follicular compartments (oocyte, granulosa, and theca cells). Several autocrine and paracrine factors are involved in follicular growth and differentiation; their activity is present even at the time of ovulation, decreasing the gap junction communication, and stimulating the theca cell proliferation. In addition, the identification of the factors that promote follicular growth from the preantral stage to the small antral stage may provide important information for the identification for assisted reproduction techniques. |
| format | Article |
| id | doaj-art-e90c0b3d7065439ebada406dc9e9a261 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-e90c0b3d7065439ebada406dc9e9a2612025-02-03T01:33:09ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/938138938138Biology and Biotechnology of Follicle DevelopmentGustavo Adolfo Palma0Martin Eduardo Argañaraz1Antonio Daniel Barrera2Daniela Rodler3Adrian Ángel Mutto4Fred Sinowatz5CICyTTP, CONICET, Dr. Materi y España s/n Entre Ríos, 3105 Diamante, ArgentinaInstituto de Biología, Facultad de Bioquímica, Universidad Nacional de Tucumán, Ayacucho 491, 4000 San Miguel de Tucumán, ArgentinaInstituto de Biología, Facultad de Bioquímica, Universidad Nacional de Tucumán, Ayacucho 491, 4000 San Miguel de Tucumán, ArgentinaInstitute of Anatomy, Histology and Embryology, Department of Veterinary Sciences, University of Munich, Veterinaerstrasse 13, 80539 Munich, GermanyBiotecnología Aplicadas a la Reproducción Animal en IIB-INTECH, Camino Laguna Km 6 B7130IWA Chascomús, ArgentinaInstitute of Anatomy, Histology and Embryology, Department of Veterinary Sciences, University of Munich, Veterinaerstrasse 13, 80539 Munich, GermanyGrowth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the progression into growing or atresia of the follicle is made. Follicular growth during this period is tightly regulated by oocyte-granulosatheca cell interactions. A cluster of early expressed genes is required for normal folliculogenesis. Granulosa cell factors stimulate the recruitment of theca cells from cortical stromal cells. Thecal factors promote granulosa cell proliferation and suppress granulosa cell apoptosis. Cell-cell and cell-extracellular matrix interactions influence the production of growth factors in the different follicular compartments (oocyte, granulosa, and theca cells). Several autocrine and paracrine factors are involved in follicular growth and differentiation; their activity is present even at the time of ovulation, decreasing the gap junction communication, and stimulating the theca cell proliferation. In addition, the identification of the factors that promote follicular growth from the preantral stage to the small antral stage may provide important information for the identification for assisted reproduction techniques.http://dx.doi.org/10.1100/2012/938138 |
| spellingShingle | Gustavo Adolfo Palma Martin Eduardo Argañaraz Antonio Daniel Barrera Daniela Rodler Adrian Ángel Mutto Fred Sinowatz Biology and Biotechnology of Follicle Development The Scientific World Journal |
| title | Biology and Biotechnology of Follicle Development |
| title_full | Biology and Biotechnology of Follicle Development |
| title_fullStr | Biology and Biotechnology of Follicle Development |
| title_full_unstemmed | Biology and Biotechnology of Follicle Development |
| title_short | Biology and Biotechnology of Follicle Development |
| title_sort | biology and biotechnology of follicle development |
| url | http://dx.doi.org/10.1100/2012/938138 |
| work_keys_str_mv | AT gustavoadolfopalma biologyandbiotechnologyoffollicledevelopment AT martineduardoarganaraz biologyandbiotechnologyoffollicledevelopment AT antoniodanielbarrera biologyandbiotechnologyoffollicledevelopment AT danielarodler biologyandbiotechnologyoffollicledevelopment AT adrianangelmutto biologyandbiotechnologyoffollicledevelopment AT fredsinowatz biologyandbiotechnologyoffollicledevelopment |