Bronchial atypical carcinoid in the truncus intermedius persistently controlled by PDT following transbronchial resection instead of surgery: A case report
Atypical carcinoids (ACs) are rare malignant types of neuroendocrine tumors, accounting for approximately 10–15% of carcinoid neoplasms of the lung. They manifest a higher trend of recurrence and metastasis in comparison with typical carcinoids (TCs). PDT is effective and safe for patients with earl...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025001140 |
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| Summary: | Atypical carcinoids (ACs) are rare malignant types of neuroendocrine tumors, accounting for approximately 10–15% of carcinoid neoplasms of the lung. They manifest a higher trend of recurrence and metastasis in comparison with typical carcinoids (TCs). PDT is effective and safe for patients with early-stage central lung cancer, but there are few reports of its application for ACs. The gold standard treatment for bronchial carcinoid is surgery. Endobronchial treatment (EBT) has recently become an option for intraluminal TCs, but EBT for ACs is vague. We report on a45-year-old woman with hemoptysis, diagnosed with AC localized in the truncus intermedius, who underwent photodynamic therapy (PDT) following transbronchial resection instead of surgery, and has survived long-term without recurrence. In our case, PDT induced tumor necrosis and has achieved local control. We avoided a larger surgical procedure and improved the patient's quality of life. PDT may become a treatment options for small intraluminal AC after further clinical trials. |
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| ISSN: | 1572-1000 |