Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review
Linezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom th...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2013/535616 |
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| _version_ | 1832560774343557120 |
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| author | Alena Tse-Chang Dennis Kunimoto Evelina Der Rabia Ahmed |
| author_facet | Alena Tse-Chang Dennis Kunimoto Evelina Der Rabia Ahmed |
| author_sort | Alena Tse-Chang |
| collection | DOAJ |
| description | Linezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects. The present study adds to the growing evidence supporting the efficacy of linezolid for tuberculosis, although treatment remains complicated by adverse effects. |
| format | Article |
| id | doaj-art-e8fe1904b2f34cb1b299299016b230b9 |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-e8fe1904b2f34cb1b299299016b230b92025-02-03T01:26:49ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-01243e50e5210.1155/2013/535616Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case ReviewAlena Tse-Chang0Dennis Kunimoto1Evelina Der2Rabia Ahmed3Department of Pediatrics, University of Alberta, Edmonton, Alberta, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaCentral TB Services, Alberta Health Services, Edmonton, Alberta, CanadaDepartment of Medicine, University of Alberta, Edmonton, Alberta, CanadaLinezolid is a potentially effective drug for the treatment of patients with drug-resistant tuberculosis. Among 13 patients treated for tuberculosis with linezolid in the present study, nine had treatment success and four remain on treatment. Adverse effects occurred in 11 (85%) patients, of whom three discontinued treatment because of adverse effects. The present study adds to the growing evidence supporting the efficacy of linezolid for tuberculosis, although treatment remains complicated by adverse effects.http://dx.doi.org/10.1155/2013/535616 |
| spellingShingle | Alena Tse-Chang Dennis Kunimoto Evelina Der Rabia Ahmed Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review |
| title_full | Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review |
| title_fullStr | Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review |
| title_full_unstemmed | Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review |
| title_short | Assessment of Linezolid Efficacy, Safety and Tolerability in the Treatment of Tuberculosis: A Retrospective Case Review |
| title_sort | assessment of linezolid efficacy safety and tolerability in the treatment of tuberculosis a retrospective case review |
| url | http://dx.doi.org/10.1155/2013/535616 |
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